Detail publikace

The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

Originální název

The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

Anglický název

The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

Jazyk

en

Originální abstrakt

Metallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance the expression of MT-3 or protect it from degradation is an attractive therapeutic target, because low levels of MT-3 were found in brains of Alzheimer's disease (AD) patients.

Anglický abstrakt

Metallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance the expression of MT-3 or protect it from degradation is an attractive therapeutic target, because low levels of MT-3 were found in brains of Alzheimer's disease (AD) patients.

Plný text v Digitální knihovně

BibTex


@article{BUT139120,
  author="Sudeep {Roy} and Jaromír {Gumulec} and Akhil {Kumar} and Martina {Raudenská} and Mohd Hassan {Baig} and Hana {Polanská} and Jan {Balvan} and Mansi {Gupta} and Petr {Babula} and Jan {Odstrčilík} and Inho {Choi} and Ivo {Provazník} and Michal {Masařík}",
  title="The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease",
  annote="Metallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance the expression of MT-3 or protect it from degradation is an attractive therapeutic target, because low levels of MT-3 were found in brains of Alzheimer's disease (AD) patients.",
  address="Wiley Periodicals",
  chapter="139120",
  doi="10.1002/brb3.799",
  howpublished="online",
  institution="Wiley Periodicals",
  number="9",
  volume="7",
  year="2017",
  month="august",
  pages="1--9",
  publisher="Wiley Periodicals",
  type="journal article in Web of Science"
}