Detail publikace

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

ČAPKA, L. ZLÁMALOVÁ GARGOŠOVÁ, H. VÁVROVÁ, M.

Originální název

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

Anglický název

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

Jazyk

en

Originální abstrakt

This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.

Anglický abstrakt

This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.

Dokumenty

BibTex 


@article{BUT119157,
  author="Lukáš {Čapka} and Helena {Zlámalová Gargošová} and Milada {Vávrová}",
  title="Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs",
  annote="This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.",
  chapter="119157",
  howpublished="print",
  number="12",
  volume="24",
  year="2015",
  month="december",
  pages="4758--4762",
  type="journal article in Web of Science"
}