Detail publikace

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

NEUŽIL, P. Camila Campos, Wong, C, Soon, J. Reboud, J, Manz, A.

Originální název

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

Anglický název

From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)

Jazyk

en

Originální abstrakt

We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing system. We demonstrate different configurations to perform most detection schemes currently in use in LOC systems, including some of the most advanced such as nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and realtime PCR. The complete system is controlled by a single chip and the collected information is stored in situ, with the option of transferring the data to an external display by using a USB interface. In addition to providing a framework for truly portable real-life developments of LOC systems, we envisage that this system will have a significant impact on education, especially since it can easily demonstrate the benefits of integrated microanalytical systems.

Anglický abstrakt

We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical current detection that serves as the sensing system. We demonstrate different configurations to perform most detection schemes currently in use in LOC systems, including some of the most advanced such as nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and realtime PCR. The complete system is controlled by a single chip and the collected information is stored in situ, with the option of transferring the data to an external display by using a USB interface. In addition to providing a framework for truly portable real-life developments of LOC systems, we envisage that this system will have a significant impact on education, especially since it can easily demonstrate the benefits of integrated microanalytical systems.

Plný text v Digitální knihovně

Dokumenty

BibTex


@article{BUT115141,
  author="Pavel {Neužil}",
  title="From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC)",
  annote="We present a portable, battery-operated and application-specific lab-on-a-chip (ASLOC) system that can
be easily configured for a wide range of lab-on-a-chip applications. It is based on multiplexed electrical
current detection that serves as the sensing system. We demonstrate different configurations to perform
most detection schemes currently in use in LOC systems, including some of the most advanced such as
nanowire-based biosensing, surface plasmon resonance sensing, electrochemical detection and realtime
PCR. The complete system is controlled by a single chip and the collected information is stored
in situ, with the option of transferring the data to an external display by using a USB interface. In addition
to providing a framework for truly portable real-life developments of LOC systems, we envisage that this
system will have a significant impact on education, especially since it can easily demonstrate the benefits
of integrated microanalytical systems.",
  address="Royal Society of Chemistry",
  chapter="115141",
  doi="10.1039/c4lc00310a",
  howpublished="online",
  institution="Royal Society of Chemistry",
  number="2168",
  volume="14",
  year="2014",
  month="march",
  pages="2168--2176",
  publisher="Royal Society of Chemistry",
  type="journal article in Web of Science"
}