Detail publikace

Isolated heart models: cardiovascular system studies and technological advances

Originální název

Isolated heart models: cardiovascular system studies and technological advances

Anglický název

Isolated heart models: cardiovascular system studies and technological advances

Jazyk

en

Originální abstrakt

Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.

Anglický abstrakt

Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.

BibTex


@article{BUT113338,
  author="Veronika {Olejníčková} and Marie {Nováková} and Ivo {Provazník}",
  title="Isolated heart models: cardiovascular system studies and technological advances",
  annote="Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.",
  address="Springer",
  chapter="113338",
  doi="10.1007/s11517-015-1270-2",
  institution="Springer",
  number="3",
  volume="2015",
  year="2015",
  month="march",
  pages="1--9",
  publisher="Springer",
  type="journal article in Web of Science"
}