Detail publikace

Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements

KYNCLOVÁ, H. PŘIBYL, J. HRDÝ, R. DRBOHLAVOVÁ, J. PRÁŠEK, J. HUBÁLEK, J.

Originální název

Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Doxorubicin is a planar aromatic molecule and it is commonly used in cancer chemotherapy. In this study, we compared nanostructured electrodes with gold nanocolumns and flat gold electrodes by measurements with doxorubicin. Nanostructured electrodes were fabricated by electrochemical anodic oxidation when the aluminium layer was transformed to the porous alumina layer. Then gold material was deposited into the pores. After removal of aluminium template the nanostructured surface made of ordered gold nanocolumns on metal underlay was obtained. Flat gold electrodes were fabricated by evaporation of gold layer to the silicon substrate. After that, all electrodes were characterized by electrochemical impedance spectroscopy and then the detection of doxorubicin was studied by differential pulse voltammetry. According to the impedance spectroscopy measurements a bigger electroactive area for nanostructured electrodes was proved. The gold nanocolumns have been found as a significant factor in increasing of electrodes active area. This fact is very important for sensors sensitivity. Fabricated electrodes were successfully used for determination of doxorubicin. Doxorubicin oxidation peak was observed at a potential - 0.6 V.

Klíčová slova

gold nanocolumns, impedance spectroscopy, differential pulse voltammetry, doxorubicin

Autoři

KYNCLOVÁ, H.; PŘIBYL, J.; HRDÝ, R.; DRBOHLAVOVÁ, J.; PRÁŠEK, J.; HUBÁLEK, J.

Rok RIV

2013

Vydáno

16. 10. 2013

Nakladatel

Tanger, Ltd.

Místo

Ostrava

ISBN

978-80-87294-47-5

Kniha

Conference Proceedings 5th International Conference NANOCON 2013

Strany od

215

Strany do

219

Strany počet

5

BibTex

@inproceedings{BUT102059,
  author="Hana {Kynclová} and Jakub {Přibyl} and Radim {Hrdý} and Jana {Drbohlavová} and Jan {Prášek} and Jaromír {Hubálek}",
  title="Comparison of gold nanostructured electrode and flat gold electrode on doxorubicin measurements",
  booktitle="Conference Proceedings 5th International Conference NANOCON 2013",
  year="2013",
  pages="215--219",
  publisher="Tanger, Ltd.",
  address="Ostrava",
  isbn="978-80-87294-47-5"
}