Detail publikace

Sarcosine as a potential prostate cancer biomarker – A review

CERNEI, N. HEGER, Z. GUMULEC, J. ZÍTKA, O. MASAŘÍK, M. BABULA, P. ECKSCHLAGER, T. STIBOROVÁ, M. KIZEK, R. ADAM, V.

Originální název

Sarcosine as a potential prostate cancer biomarker – A review

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Prostate cancer (CaP) is the most common type of tumour disease in men. Early diagnosis of cancer of the prostate is very important, because the sooner the cancer is detected, the better it is treated. According to that fact, there is great interest in the finding of new markers including amino acids, proteins or nucleic acids. Prostate specific antigen (PSA) is commonly used and is the most important biomarker of CaP. This marker can only be detected in blood and its sensitivity is approximately 80%. Moreover, early stages cannot be diagnosed using this protein. Currently, there does not exist a test for diagnosis of early stages of prostate cancer. This fact motivates us to find markers sensitive to the early stages of CaP, which are easily detected in body fluids including urine

Klíčová slova

Prostate cancer, markers, prostate specific antigen, biomarker, urine

Autoři

CERNEI, N.; HEGER, Z.; GUMULEC, J.; ZÍTKA, O.; MASAŘÍK, M.; BABULA, P.; ECKSCHLAGER, T.; STIBOROVÁ, M.; KIZEK, R.; ADAM, V.

Rok RIV

2013

Vydáno

4. 7. 2013

Nakladatel

MDPI

ISSN

1422-0067

Periodikum

International Journal of Molecular Sciences

Ročník

14

Číslo

7

Stát

Švýcarská konfederace

Strany od

13893

Strany do

13908

Strany počet

15

URL

http://www.mdpi.com/1422-0067/14/7/13893

Plný text v Digitální knihovně

http://hdl.handle.net/11012/70084

BibTex

@article{BUT100938,
  author="Natalia Vladimirovna {Cernei} and Zbyněk {Heger} and Jaromír {Gumulec} and Ondřej {Zítka} and Michal {Masařík} and Petr {Babula} and Tomáš {Eckschlager} and Marie {Stiborová} and René {Kizek} and Vojtěch {Adam}",
  title="Sarcosine as a potential prostate cancer biomarker – A review",
  journal="International Journal of Molecular Sciences",
  year="2013",
  volume="14",
  number="7",
  pages="13893--13908",
  doi="10.3390/ijms140713893",
  issn="1422-0067",
  url="http://www.mdpi.com/1422-0067/14/7/13893"
}