Detail publikace

Influence of injection speed of contrast agent on perfusion analysis using fast bolus method

HARABIŠ, V. KOLÁŘ, R. MÉZL, M.

Originální název

Influence of injection speed of contrast agent on perfusion analysis using fast bolus method

Český název

Influence of injection speed of contrast agent on perfusion analysis using fast bolus method

Anglický název

Influence of injection speed of contrast agent on perfusion analysis using fast bolus method

Typ

článek ve sborníku

Jazyk

en

Originální abstrakt

Dynamic contrast enhanced ultrasound (DCE-US) imaging is a promising modality for noninvasive assessment of various tissue kinetic parameters (e.g. time-to-peak, mean transit time (MTT), blood flow etc.). These parameters can be used for diagnosis of pathological tissue functions caused by different diseases. Fast bolus method is based on the fast injection of bolus of contrast agent and repeated imaging with low MI to track contrast agent in tissue of interest (TOI) in time. Mathematical model fitting is an important part of this analysis, which usually presumes that injected bolus is infinitely short, but in practice this is impossible. The main aim of this paper is an analysis of influence of bolus injection rate on MTT estimated by different fitting model. We discover that using a finite-width bolus causes systematic error in MTT estimation.

Český abstrakt

Dynamic contrast enhanced ultrasound (DCE-US) imaging is a promising modality for noninvasive assessment of various tissue kinetic parameters (e.g. time-to-peak, mean transit time (MTT), blood flow etc.). These parameters can be used for diagnosis of pathological tissue functions caused by different diseases. Fast bolus method is based on the fast injection of bolus of contrast agent and repeated imaging with low MI to track contrast agent in tissue of interest (TOI) in time. Mathematical model fitting is an important part of this analysis, which usually presumes that injected bolus is infinitely short, but in practice this is impossible. The main aim of this paper is an analysis of influence of bolus injection rate on MTT estimated by different fitting model. We discover that using a finite-width bolus causes systematic error in MTT estimation.

Anglický abstrakt

Dynamic contrast enhanced ultrasound (DCE-US) imaging is a promising modality for noninvasive assessment of various tissue kinetic parameters (e.g. time-to-peak, mean transit time (MTT), blood flow etc.). These parameters can be used for diagnosis of pathological tissue functions caused by different diseases. Fast bolus method is based on the fast injection of bolus of contrast agent and repeated imaging with low MI to track contrast agent in tissue of interest (TOI) in time. Mathematical model fitting is an important part of this analysis, which usually presumes that injected bolus is infinitely short, but in practice this is impossible. The main aim of this paper is an analysis of influence of bolus injection rate on MTT estimated by different fitting model. We discover that using a finite-width bolus causes systematic error in MTT estimation.

Klíčová slova

ultrasound, contrast agent, perfusion analysis

Rok RIV

2012

Vydáno

10.10.2012

ISBN

978-1-4577-1253-1

Kniha

Proceedings of the IEEE International Ultrasonics Symposium 2012, Dresden

Strany od

1319

Strany do

1322

Strany počet

4

BibTex


@inproceedings{BUT94788,
  author="Vratislav {Harabiš} and Radim {Kolář} and Martin {Mézl}",
  title="Influence of injection speed of contrast agent on perfusion analysis using fast bolus method",
  annote="Dynamic  contrast  enhanced  ultrasound  (DCE-US)
imaging is a promising modality for noninvasive assessment of
various tissue kinetic parameters (e.g. time-to-peak, mean transit
time  (MTT),  blood  flow  etc.).  These  parameters  can  be  used
for diagnosis of pathological tissue functions caused by different
diseases. Fast bolus method is based on the fast injection of bolus
of contrast agent and repeated imaging with low MI to track
contrast agent in tissue of interest (TOI) in time. Mathematical
model fitting is an important part of this analysis, which usually
presumes that injected bolus is infinitely short, but in practice
this is impossible. The main aim of this paper is an analysis of
influence of bolus injection rate on MTT estimated by different
fitting model. We discover that using a finite-width bolus causes
systematic error in MTT estimation.",
  booktitle="Proceedings of the IEEE International Ultrasonics Symposium 2012, Dresden",
  chapter="94788",
  howpublished="online",
  year="2012",
  month="october",
  pages="1319--1322",
  type="conference paper"
}