Detail publikace

DNA-doxorubicin interactions revealed by electrochemistry

Originální název

DNA-doxorubicin interactions revealed by electrochemistry

Anglický název

DNA-doxorubicin interactions revealed by electrochemistry

Jazyk

en

Originální abstrakt

Anthracyclines including doxorubicin are commonly used in the treatment of a number of diverse malignant tumours - acute leukaemia, non-Hodgkin and Hodgkin lymphoma and several solid tumours including neuroblastoma. The aim of this study was to compare effects of doxorubicin on sensitive and resistant cells by using electrochemical and mathematical methods. We compared differences between signals of DNA isolated from sensitive and resistant tumour cells by statistical models.

Anglický abstrakt

Anthracyclines including doxorubicin are commonly used in the treatment of a number of diverse malignant tumours - acute leukaemia, non-Hodgkin and Hodgkin lymphoma and several solid tumours including neuroblastoma. The aim of this study was to compare effects of doxorubicin on sensitive and resistant cells by using electrochemical and mathematical methods. We compared differences between signals of DNA isolated from sensitive and resistant tumour cells by statistical models.

BibTex


@misc{BUT93604,
  author="Michal {Masařík} and Hana {Kynclová} and Dalibor {Húska} and Jaromír {Hubálek} and Vojtěch {Adam} and Petr {Babula} and René {Kizek}",
  title="DNA-doxorubicin interactions revealed by electrochemistry",
  annote="Anthracyclines including doxorubicin are commonly used in the treatment of a number of diverse malignant tumours - acute leukaemia, non-Hodgkin and Hodgkin lymphoma and several solid tumours including neuroblastoma. The aim of this study was to compare effects of doxorubicin on sensitive and resistant cells by using electrochemical and mathematical methods. We compared differences between signals of DNA isolated from sensitive and resistant tumour cells by statistical models.",
  address="INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE",
  chapter="93604",
  institution="INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE",
  number="1",
  year="2010",
  month="january",
  pages="S46--S46",
  publisher="INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE",
  type="abstract"
}