Detail publikace

Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review

Originální název

Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review

Anglický název

Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review

Jazyk

en

Originální abstrakt

The electroactivity of DNA was discovered in 1958 by Emil Palecek. Since than, there have been done great progress and development in electrochemistry of nucleic acids at various electrodes. In this review, after brief overview of milestones in research in electrochemistry, history of electroanalysis of DNA follows. Then, the attention is aimed at various electrochemical methods using a mercury electrode as a working one including linear sweep and cyclic polarography/voltammetry (elimination polarography/voltammetry), differential pulse polarography/voltammetry, square wave polarography/voltammetry, AC polarography/voltammetry and chronopotentiometry for analysis of DNA. Coupling of adsorptive transfer stripping technique to the above-mentioned methods is very promising for nucleic acid studying and is discussed. Further, advantages of mercury and amalgam electrodes are mentioned. The advantages of coupling of electroanalysis of DNA at mercury electrodes with paramagnetic particles based isolation of target molecules are shown.

Anglický abstrakt

The electroactivity of DNA was discovered in 1958 by Emil Palecek. Since than, there have been done great progress and development in electrochemistry of nucleic acids at various electrodes. In this review, after brief overview of milestones in research in electrochemistry, history of electroanalysis of DNA follows. Then, the attention is aimed at various electrochemical methods using a mercury electrode as a working one including linear sweep and cyclic polarography/voltammetry (elimination polarography/voltammetry), differential pulse polarography/voltammetry, square wave polarography/voltammetry, AC polarography/voltammetry and chronopotentiometry for analysis of DNA. Coupling of adsorptive transfer stripping technique to the above-mentioned methods is very promising for nucleic acid studying and is discussed. Further, advantages of mercury and amalgam electrodes are mentioned. The advantages of coupling of electroanalysis of DNA at mercury electrodes with paramagnetic particles based isolation of target molecules are shown.

BibTex


@article{BUT72550,
  author="David {Hynek} and Jan {Prášek} and Jana {Pekárková} and Libuše {Trnková} and Vojtěch {Adam} and Jaromír {Hubálek} and René {Kizek}",
  title="Advantages and progress in the analysis of DNA by using mercury and amalgam electrodes - Review",
  annote="The electroactivity of DNA was discovered in 1958 by Emil Palecek. Since than, there have been done great progress and development in electrochemistry of nucleic acids at various electrodes. In this review, after brief overview of milestones in research in electrochemistry, history of electroanalysis of DNA follows. Then, the attention is aimed at various electrochemical methods using a mercury electrode as a working one including linear sweep and cyclic polarography/voltammetry (elimination polarography/voltammetry), differential pulse polarography/voltammetry, square wave polarography/voltammetry, AC polarography/voltammetry and chronopotentiometry for analysis of DNA. Coupling of adsorptive transfer stripping technique to the above-mentioned methods is very promising for nucleic acid studying and is discussed. Further, advantages of mercury and amalgam electrodes are mentioned. The advantages of coupling of electroanalysis of DNA at mercury electrodes with paramagnetic particles based isolation of target molecules are shown.",
  address="Bentham Science Publishers Ltd.",
  chapter="72550",
  institution="Bentham Science Publishers Ltd.",
  number="4",
  volume="1",
  year="2011",
  month="may",
  pages="299--324",
  publisher="Bentham Science Publishers Ltd.",
  type="journal article - other"
}