Detail publikace

Genomic PCR simulation with hardware-accelerated approximate sequence matching

Originální název

Genomic PCR simulation with hardware-accelerated approximate sequence matching

Anglický název

Genomic PCR simulation with hardware-accelerated approximate sequence matching

Jazyk

en

Originální abstrakt

We report the latest details on improvements made or planned for the VPCR simulation software currently accessible on the Internet. We describe the inner workings of the dynamic amplification simulation model, concentrating mostly on the time- and sensitivity-critical step of sequence matching. Replacement of BLAST by the more sensitive and faster PRIMEX similarity search program resulted in a marked improvement of PCR product predictions. Further speed improvements were acheived using hardware acceleration of approximate sequence matching.

Anglický abstrakt

We report the latest details on improvements made or planned for the VPCR simulation software currently accessible on the Internet. We describe the inner workings of the dynamic amplification simulation model, concentrating mostly on the time- and sensitivity-critical step of sequence matching. Replacement of BLAST by the more sensitive and faster PRIMEX similarity search program resulted in a marked improvement of PCR product predictions. Further speed improvements were acheived using hardware acceleration of approximate sequence matching.

BibTex


@inproceedings{BUT26056,
  author="Matej {Lexa} and Tomáš {Martínek} and Patrik {Beck} and Otto {Fučík} and Giorgio {Valle} and Ivano {Zara}",
  title="Genomic PCR simulation with hardware-accelerated approximate sequence matching",
  annote="We report the latest details on improvements made or planned for the VPCR
simulation software currently accessible on the Internet. We describe the inner
workings of the dynamic amplification simulation model, concentrating mostly on
the time- and sensitivity-critical step of sequence matching. Replacement of
BLAST by the more sensitive and faster PRIMEX similarity search program resulted
in a marked improvement of PCR product predictions. Further speed improvements
were acheived using hardware acceleration of approximate sequence matching.",
  address="European Council for Modelling and Simulation",
  booktitle="21st European Conference on Modelling and Simulation",
  chapter="26056",
  howpublished="print",
  institution="European Council for Modelling and Simulation",
  year="2007",
  month="june",
  pages="333--338",
  publisher="European Council for Modelling and Simulation",
  type="conference paper"
}