Detail publikace

Application of molecularly imprinted polymers as artificial receptors for imaging

VANĚČKOVÁ, T. BEZDĚKOVÁ, J. HAN, G. ADAM, V. VACULOVIČOVÁ, M.

Originální název

Application of molecularly imprinted polymers as artificial receptors for imaging

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Medical diagnostics aims at specific localization of molecular targets as well as detection of abnormalities associated with numerous diseases. Molecularly imprinted polymers (MIPs) represent an approach of creating a synthetic material exhibiting selective recognition properties toward the desired template. The fabricated target-specific MIPs are usually well reproducible, economically efficient, and stable under critical conditions as compared to routinely used biorecognition elements such as fluorescent proteins, antibodies, enzymes, or aptamers and can even be created to those targets for which no antibodies are available. In this review, we summarize the methods of polymer fabrication. Further, we provide key for selection of the core material with imaging function depending on the imaging modality used. Finally, MIP-based imaging applications are highlighted and presented in a comprehensive form from different aspects.

Klíčová slova

Luminescence; Polymerization; Microscopy; Affinity

Autoři

VANĚČKOVÁ, T.; BEZDĚKOVÁ, J.; HAN, G.; ADAM, V.; VACULOVIČOVÁ, M.

Vydáno

1. 1. 2020

ISSN

1742-7061

Periodikum

Acta Biomaterialia

Ročník

101

Číslo

1

Stát

Spojené království Velké Británie a Severního Irska

Strany od

444

Strany do

458

Strany počet

15

URL

BibTex

@article{BUT161332,
  author="Tereza {Vaněčková} and Jaroslava {Bezděková} and Gang {Han} and Vojtěch {Adam} and Markéta {Vaculovičová}",
  title="Application of molecularly imprinted polymers as artificial receptors for imaging",
  journal="Acta Biomaterialia",
  year="2020",
  volume="101",
  number="1",
  pages="444--458",
  doi="10.1016/j.actbio.2019.11.007",
  issn="1742-7061",
  url="https://www.sciencedirect.com/science/article/pii/S1742706119307470"
}