Detail publikace

Generation of humanized bone-marrow-like niche in immunodeficient mice

ČULEN, M. KOSAŘOVÁ, Z. SOKOL, F. CHOVANCOVÁ, J. DVOŘÁKOVÁ, D. VOJTOVÁ, L. RÁČIL, Z.

Originální název

Generation of humanized bone-marrow-like niche in immunodeficient mice

Typ

konferenční sborník (ne článek)

Jazyk

angličtina

Originální abstrakt

Imunodeficient mice represent a standard in vivo model for study of different types of human leukemias. Not all leukemic cells, however, do engraft/proliferate after xenotransplantation to mice, which is supposedly caused by inter-species differences. This problem can be resolved by introducing a humanized microenvironment into the animal recipients, via sub-cutaneous implantation of a suitable biomaterial and human mesenchymal stromal cells (MSC).

Klíčová slova

bone-marrow, immunodeficient mice, collagen scaffold, mesenchymal stomal cells

Autoři

ČULEN, M.; KOSAŘOVÁ, Z.; SOKOL, F.; CHOVANCOVÁ, J.; DVOŘÁKOVÁ, D.; VOJTOVÁ, L.; RÁČIL, Z.

Vydáno

20. 4. 2017

Nakladatel

Symma s.r.o.

Místo

Brno

Strany od

41

Strany do

41

Strany počet

62

BibTex

@proceedings{BUT145082,
  editor="Martin {Čulen} and Zdeňka {Kosařová} and Filip {Sokol} and Jana {Chovancová} and Dana {Dvořáková} and Lucy {Vojtová} and Zdeněk {Ráčil}",
  title="Generation of humanized bone-marrow-like niche in immunodeficient mice",
  year="2017",
  pages="41--41",
  publisher="Symma s.r.o.",
  address="Brno"
}