Detail publikace

Advanced Microrheological Techniques In The Research Of Hydrogels

JARÁBKOVÁ, S. KÁBRTOVÁ, P. MRAVEC, F. PEKAŘ, M.

Originální název

Advanced Microrheological Techniques In The Research Of Hydrogels

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

This work is focused on the use of advanced fluorescence correlation spectroscopy technique (FCS) in microrheological characterization of hydrogels. Hydrogels were prepared from negatively charged polymer (sodium hyaluronate) and oppositely charged surfactant (cetyltrimethylammonium bromide) in physiological environment. Low, medium and high molecular weight sodium hyaluronate was used. Our hydrogels contain more than 90 % of water and they are able to solubilize hydrophobic and hydrophilic species. These hydrogels contain hydrophobic nanodomains (nanocontainers) and can be promising materials for the use in many applications, e.g. in topical applications or local drug delivery systems. Main aim of this work is to study microrhelological behavior of these systems and usability of FCS technique in these systems. For microrheological FCS analysis were used fluorescently labelled particles. Optimum particle size was selected based on analysis of Newtonian glycerol solutions. The results of FCS hydrogel microrheology were compared with the measurement of hyaluronan solutions. Concentration and molecular weight of this biopolymer were monitored.

Klíčová slova

hydrogels, fluorescence correlation spectroscopy (FCS), nanocontainers, surfactants

Autoři

JARÁBKOVÁ, S.; KÁBRTOVÁ, P.; MRAVEC, F.; PEKAŘ, M.

Vydáno

10. 9. 2017

Nakladatel

Johan Hofkens, Maarten Roeffaers & Kris Janssen

Místo

Bruggy, Belgie

Strany od

211

Strany do

211

Strany počet

1

BibTex

@misc{BUT139921,
  author="Sabína {Jarábková} and Petra {Kábrtová} and Filip {Mravec} and Miloslav {Pekař}",
  title="Advanced Microrheological Techniques In The Research Of Hydrogels",
  booktitle="Abstract book",
  year="2017",
  series="1",
  edition="1",
  pages="211--211",
  publisher="Johan Hofkens, Maarten Roeffaers & Kris Janssen",
  address="Bruggy, Belgie",
  note="abstract"
}