Detail publikace

The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

ROY, S. GUMULEC, J. KUMAR, A. RAUDENSKÁ, M. BAIG, M. POLANSKÁ, H. BALVAN, J. GUPTA, M. BABULA, P. ODSTRČILÍK, J. CHOI, I. PROVAZNÍK, I. MASAŘÍK, M.

Originální název

The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Metallothioneins (MTs) are a class of ubiquitously occurring low-molecular-weight cysteine- and metal-rich proteins containing sulfur-based metal clusters. MT-3 exhibits neuro-inhibitory activity. The possibility to enhance the expression of MT-3 or protect it from degradation is an attractive therapeutic target, because low levels of MT-3 were found in brains of Alzheimer's disease (AD) patients.

Klíčová slova

Alzheimer’s Disease, Flow Cytometry, Immunodetection, Metallothionein-3, Molecular Dynamics, qRT-PCR

Autoři

ROY, S.; GUMULEC, J.; KUMAR, A.; RAUDENSKÁ, M.; BAIG, M.; POLANSKÁ, H.; BALVAN, J.; GUPTA, M.; BABULA, P.; ODSTRČILÍK, J.; CHOI, I.; PROVAZNÍK, I.; MASAŘÍK, M.

Vydáno

15. 8. 2017

Nakladatel

Wiley Periodicals

Místo

New York, USA

ISSN

2162-3279

Periodikum

Brain and Behavior

Ročník

7

Číslo

9

Stát

Spojené státy americké

Strany od

1

Strany do

9

Strany počet

9

URL

http://onlinelibrary.wiley.com/doi/10.1002/brb3.799/abstract

Plný text v Digitální knihovně

http://hdl.handle.net/11012/69945

BibTex

@article{BUT139120,
  author="Sudeep {Roy} and Jaromír {Gumulec} and Akhil {Kumar} and Martina {Raudenská} and Mohd Hassan {Baig} and Hana {Polanská} and Jan {Balvan} and Mansi {Gupta} and Petr {Babula} and Jan {Odstrčilík} and Inho {Choi} and Valentine {Provazník} and Michal {Masařík}",
  title="The effect of Benzothiazolone-2 on the expression of Metallothionein-3 in modulating Alzheimer's disease",
  journal="Brain and Behavior",
  year="2017",
  volume="7",
  number="9",
  pages="1--9",
  doi="10.1002/brb3.799",
  issn="2162-3279",
  url="http://onlinelibrary.wiley.com/doi/10.1002/brb3.799/abstract"
}