Detail publikace

Molecular docking study of potential drug candidates against borreliosis

KOŠČOVÁ, P.

Originální název

Molecular docking study of potential drug candidates against borreliosis

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Lyme borreliosis is one of the most common tick-borne infections, for which there is an extensive need to find a new drug. For this purpose our in silicodocking study was carried out to identify drug-likeness of chosen small molecules –potential borreliosis drugs. Its results revealed that BesA compound (C2 form) – a membrane fusion protein present in Borrelia burgdorferi, can play a significant role as a possible drug target compound and therefore it should be further examined in development of potential drugs for Lyme borreliosis treatment.

Klíčová slova

Borrelia burgdorferi, borreliosis, Lyme disease, resistance, molecular docking

Autoři

KOŠČOVÁ, P.

Vydáno

27. 4. 2017

Nakladatel

Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií

Místo

Brno

ISBN

978-80-214-5496-5

Kniha

Proceedings of the 23rd Conference STUDENT EEICT 2017

Strany od

339

Strany do

343

Strany počet

5

BibTex

@inproceedings{BUT135396,
  author="Pavlína {Cicková}",
  title="Molecular docking study of potential drug candidates against borreliosis",
  booktitle="Proceedings of the 23rd Conference STUDENT EEICT 2017",
  year="2017",
  pages="339--343",
  publisher="Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií",
  address="Brno",
  isbn="978-80-214-5496-5"
}