Detail publikace

MHC AND KIR GENOTYPING OF MACAQUES IN HIV INFECTION RESEARCH

MATULA, J.

Originální název

MHC AND KIR GENOTYPING OF MACAQUES IN HIV INFECTION RESEARCH

Anglický název

MHC AND KIR GENOTYPING OF MACAQUES IN HIV INFECTION RESEARCH

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

čeština

Originální abstrakt

Modern research of viral diseases relies on genomic data processing. Not only is the sequence of a virus important, genomic sequence of specific receptors in affected organisms also plays an important role. In this paper, a novel package for processing of next generation sequencing data in infectious disease written using R/Bioconductor language is proposed. Functionality of the package, including implementation of advanced SSAHA algorithm for fast database searches, in demonstrated using genotyping of genes for MHC and KIR receptors of HIV positive macaques.

Anglický abstrakt

Modern research of viral diseases relies on genomic data processing. Not only is the sequence of a virus important, genomic sequence of specific receptors in affected organisms also plays an important role. In this paper, a novel package for processing of next generation sequencing data in infectious disease written using R/Bioconductor language is proposed. Functionality of the package, including implementation of advanced SSAHA algorithm for fast database searches, in demonstrated using genotyping of genes for MHC and KIR receptors of HIV positive macaques.

Klíčová slova

Roche 454, SSAHA, sequencing, demultiplexing, hash table, HIV, genotyping

Klíčová slova v angličtině

Roche 454, SSAHA, sequencing, demultiplexing, hash table, HIV, genotyping

Autoři

MATULA, J.

Vydáno

27. 4. 2017

ISBN

978-80-214-5496-5

Kniha

Proceedings of the 23rd Conference STUDENT EEICT 2017

Strany od

27

Strany do

29

Strany počet

3

BibTex

@inproceedings{BUT135342,
  author="Jan {Matula}",
  title="MHC AND KIR GENOTYPING OF MACAQUES IN HIV INFECTION RESEARCH",
  booktitle="Proceedings of the 23rd  Conference STUDENT EEICT 2017",
  year="2017",
  pages="27--29",
  isbn="978-80-214-5496-5"
}