Detail publikace

Multidimensional Correlated Mutation Analysis for Protein Contact Map Prediction

Originální název

Multidimensional Correlated Mutation Analysis for Protein Contact Map Prediction

Anglický název

Multidimensional Correlated Mutation Analysis for Protein Contact Map Prediction

Jazyk

en

Originální abstrakt

Correlated mutation (CM) analysis has been proved to be an important tool used in protein contact map prediction from primary amino acid sequence. Over the last years CM methods have been refined and then often combined with methods of different nature in order to improve reached precision. However, since the methods are still relatively new, only precision and improvement have been reported without mentioning recall which is very low. In this paper, we combine previously described CM analysis methods with an outcome of four new techniques which significantly increase recall for the cost of minimal precision impairment. This study is the first of our knowledge with focus on recall improvement.

Anglický abstrakt

Correlated mutation (CM) analysis has been proved to be an important tool used in protein contact map prediction from primary amino acid sequence. Over the last years CM methods have been refined and then often combined with methods of different nature in order to improve reached precision. However, since the methods are still relatively new, only precision and improvement have been reported without mentioning recall which is very low. In this paper, we combine previously described CM analysis methods with an outcome of four new techniques which significantly increase recall for the cost of minimal precision impairment. This study is the first of our knowledge with focus on recall improvement.

BibTex


@inproceedings{BUT126084,
  author="Kristýna {Kupková} and Karel {Sedlář} and Ivo {Provazník}",
  title="Multidimensional Correlated Mutation Analysis for Protein Contact Map Prediction",
  annote="Correlated mutation (CM) analysis has been proved to be an important tool used in protein contact map prediction from primary amino acid sequence. Over the last years CM methods have been refined and then often combined with methods of different nature in order to improve reached precision. However, since the methods are still relatively new, only precision and improvement have been reported without mentioning recall which is very low. In this paper, we combine previously described CM analysis methods with an outcome of four new techniques which significantly increase recall for the cost of minimal precision impairment. This study is the first of our knowledge with focus on recall improvement.",
  address="Springer International Publishing",
  booktitle="Information Technologies in Medicine, 5th International Conference, ITIB 2016 Kamień Śląski, Poland, June 20 - 22, 2016 Proceedings, Volume 2",
  chapter="126084",
  doi="10.1007/978-3-319-39904-1_12",
  howpublished="print",
  institution="Springer International Publishing",
  number="1",
  year="2016",
  month="may",
  pages="133--144",
  publisher="Springer International Publishing",
  type="conference paper"
}