Course detail

Materials for Biomedical Applications

FEKT-MKC-MBAAcad. year: 2021/2022

The course deals with materials including nanostructured ones and prepared by special technologies to be applied in biomedical praxis. Further, the action of biological environment on the corrosion and life time of materials used also the compatibility of implants in tissues will be addressed. Metrology of nanostructures such as microscopy, mass spectrometry of secondary ions and/or X-ray analysis will be explained. Recently invented electrochemical power sources designed for applications in medicine such as special diagnostic and therapeutic tools or pacemakers will be involved into a separate chapter. The chapter describing NMR for both diagnostic and analytical purposes will be also significant.

Language of instruction

Czech

Number of ECTS credits

5

Mode of study

Not applicable.

Learning outcomes of the course unit

The graduate after finishing proposed course will have be able following actions:
• Qualified judging of the materials application in biomedical praxis
• Describe the diseases of heart and vessel system and to describe the strategy of their treating
• Describe the properties of macromolecular materials, ceramics and metals suitable for implants
• To have a general survey over recent situation of materials for contact and implanted eye lenses
• To possess fundamental knowledge of usage of electrochemical power sources for laboratory equipment, cardio stimulators /peace makers and defibrillators
• To be informed of the newest trends in preparation and application of bio nanomaterials in medicine, for example, for the treatment of carcinogenous diseases
• To be avare of the nuclear magnetic spectroscopu (NMR) and of the tissues compatibility in NMR diagnostics

Prerequisites

Student who enrols this subject should be able to be able:
•to be knowledgeable in fundamental concepts of medicine
•to possess fundamental surwey of biochemical processes in living bodies
•to be able to explain essentials of elecric circuits used in biomedicine
•to be able to safely handle chemicals according to a manual

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Techning methods include lectures, practical laboratories and excursion. Course is taking advantage of e-learning (Moodle) system. Students have to write a single project/assignment during the course.

Assesment methods and criteria linked to learning outcomes

Classification of laboratory work ( 6 work assignment )...summary 30p
Written part of closing examen..............................................................60p
Presentation of assignet topic................................................................10p

Course curriculum

1. Basic physical properties of tissues and body fluids
2. Corrosion and compatibility of materials in living organisms
3. Electrodes aas sensors for analysis of tissues
4. Chemical power sources for laboratory instrumentation and implanted
devices
5. Materials for biological environment
6. Influence of ions and compounds of selected elements on composition
and properties of fluids from tissues
7. Fundamentals of NMR spectroscopy and tomography and basic
diagnostic methods
8. NMR compatibility of implantates in tissues, magnetic susceptibility of
materials

Work placements

Not applicable.

Aims

The proposed subject will prepare the pregraduate students of FEEC for the solution of technological, economic and ecologic problems connected with the choice, usage and testing of various materials in biomedical applications.

Specification of controlled education, way of implementation and compensation for absences

Exercises in laboratory are obligatory. Dully excussed absence in laboratory exercises is possible to complete after being approved by the teacher.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Sedlaříková,M. a kol. Materiály pro biomedicínu, elektronická skripta (CS)
Vondrák, J., Sedlaříková,M.,Elektrochemická měření, elektronická verze (CS)
VONDRÁK, J., SEDLAŘÍKOVÁ, M., REITER, J., NOVÁK, V., NEČESAL, P. Carbon and/ or graphite anodes for gel polymer batteries. In International Meeting on Lithium Batteries. Nara, Japonsko: The Electrochemical Society, Inc., 2004. s. 234 ( s.)ISBN: 1-56677-415- 2. (CS)
Valečko,Z: Bioelektronika, BEN Technická literatura, Praha 2005 (CS)
Navrátil,L. a kol: Medicínská biofyzika, GRADA 2005, Praha (CS)
Žabka,M. a kol.:Moderní lékové formy ve farmaceutické technologii, Bratislava 2001 (CS)

Recommended reading

Bednář B. a kol.:Nové materiály, VŠCHT, Praha 1991 (CS)
Pistoia, G.: Lithium Batteries, New Materials, Developments and Perspective, Elsevier Science B.V., Amsterodam, 1994 (EN)
Liu,B. In vitro investigation of Fe30Mn6Si shape memory alloy as potential biodegradable metallic material, Material Letters 65 (2011) 540-543 (EN)

Classification of course in study plans

  • Programme MKC-EVM Master's, 1. year of study, winter semester, compulsory-optional

Type of course unit

 

Lecture

26 hours, optionally

Teacher / Lecturer

Laboratory exercise

26 hours, compulsory

Teacher / Lecturer