Course detail

Bioinformatics

FIT-IV108Acad. year: 2019/2020

An advanced course in bioinformatics (lecture and computer lab) building upon elementary mol.biology and/or bioinformatics courses.

Learning outcomes of the course unit

Not applicable.

Prerequisites

Not applicable.

Co-requisites

Not applicable.

Recommended optional programme components

Not applicable.

Recommended or required reading

Not applicable.

Planned learning activities and teaching methods

Not applicable.

Assesment methods and criteria linked to learning outcomes

Not applicable.

Language of instruction

Czech, English

Work placements

Not applicable.

Aims

Not applicable.

Classification of course in study plans

  • Programme VTI-DR-4 Doctoral

    branch DVI4 , any year of study, winter semester, 0 credits, optional

  • Programme VTI-DR-4 Doctoral

    branch DVI4 , any year of study, winter semester, 0 credits, optional

  • Programme VTI-DR-4 Doctoral

    branch DVI4 , any year of study, winter semester, 0 credits, optional

  • Programme VTI-DR-4 Doctoral

    branch DVI4 , any year of study, winter semester, 0 credits, optional

Type of course unit

 

Lecture

13 hours, optionally

Teacher / Lecturer

Syllabus

1. Biological language (sequence segmentation, information-statistical analysis of biological sequences)
2. Pattern matching (algoritms based on filtration and suffix arrays)
3. Heuristic algorithms for similarity searching in biological sequences (BLAST, BLAT, Pattern Hunter)
4. Regular expressions in bioinformatics
5. Algorithms for analysis and prediction of structural data (secondary strukture, contacts inb proteins, domain identification)
6. Algorithms for analysis and prediction of structural data (3D structure, structural comparisons)
7. Working with molecular structures in Pymol
8. New methods of DNA sequencing
9. Genome assembly and other operations on short nucleic acid sequences
10. Prediction of melting temperature in DNA and other nucleic acids (program mfold)
11. RNA secondary structure
12. DNA computing
13. Comparative genomics of human (analysis of scientific papers)

Exercise

13 hours, compulsory

Teacher / Lecturer

eLearning