Publication detail

Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications

KUPKA, V. VOJTOVÁ, L. JANČÁŘ, J.

Original Title

Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications

English Title

Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications

Type

conference proceedings

Language

en

Original Abstract

Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzed with stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or hydrophobic PCL, were synthesized as well. It was found that mechanical properties as well as th hydrolytic stability of resulted bio-PU elastomers might be effectively tailored by both the ratio of used diols as well as by the isocyanate ratio (ratio between OH and NCO groups).

English abstract

Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzed with stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or hydrophobic PCL, were synthesized as well. It was found that mechanical properties as well as th hydrolytic stability of resulted bio-PU elastomers might be effectively tailored by both the ratio of used diols as well as by the isocyanate ratio (ratio between OH and NCO groups).

Keywords

polyurethane; elastomer; synthesis; poly(ethylene glycol), poly(caprolactone), hexamethylene diisocyanate

Released

01.09.2012

Publisher

Young Scientists Council of Polymer Institute of the Slovak Academy of Sciences

ISBN

978-80-970923-2-0

Pages from

67

Pages to

68

Pages count

106

Documents

BibTex


@proceedings{BUT95437,
  author="Vojtěch {Kupka} and Lucy {Vojtová} and Josef {Jančář}",
  title="Transparent Elastomeric Polyurethanes Based on Poly(ethylene glycol) and Poly(caprolactone) for Medical Applications",
  annote="Biodegradable polyurethane (bio-PU) elastomers with potential use as a scaffolds in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate (HMDI) catalyzed with stannous octoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 70:30, 50:50 and 30:70 were used. Samples made of one type of diol, either hydrophilic PEG or  hydrophobic PCL, were synthesized as well.
It was found that mechanical properties as well as th hydrolytic stability of resulted bio-PU elastomers might be effectively tailored by both the ratio of used diols as well as by the isocyanate ratio (ratio between OH and NCO groups).",
  address="Young Scientists Council of Polymer Institute of the Slovak Academy of Sciences",
  chapter="95437",
  institution="Young Scientists Council of Polymer Institute of the Slovak Academy of Sciences",
  year="2012",
  month="september",
  pages="67--68",
  publisher="Young Scientists Council of Polymer Institute of the Slovak Academy of Sciences",
  type="conference proceedings"
}