Publication detail

Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and nanofibres

NEČAS, A. VOJTOVÁ, L. JANČÁŘ, J.

Original Title

Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and nanofibres

English Title

Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and nanofibres

Type

journal article - other

Language

en

Original Abstract

The aim of this study was to evaluate macroscopically, histologically and immunohistochemically the quality of newly formed tissue in iatrogenic defects of articular cartilage of the femur condyle in miniature pigs treated with the clinically used method of microfractures in comparison with the transplantation of a combination of a composite scaffold with allogeneic mesenchymal stem cells (MSCs) or the composite scaffold alone.

English abstract

The aim of this study was to evaluate macroscopically, histologically and immunohistochemically the quality of newly formed tissue in iatrogenic defects of articular cartilage of the femur condyle in miniature pigs treated with the clinically used method of microfractures in comparison with the transplantation of a combination of a composite scaffold with allogeneic mesenchymal stem cells (MSCs) or the composite scaffold alone.

Keywords

collagen scaffold, bone marrow mesenchymal stem cells, Allogeneic, Micropicking, Articular cartilage

RIV year

2010

Released

20.09.2010

Publisher

Institute of Physiology,Academy of Sciences of the Czech Republic

Location

Prague, Czech Republic

Pages from

605

Pages to

614

Pages count

10

BibTex


@article{BUT50968,
  author="Alois {Nečas} and Lucy {Vojtová} and Josef {Jančář}",
  title="Quality of Newly Formed Cartilaginous Tissue in Defects of Articular Surface after Transplantation of Mesenchymal Stem Cells in a Composite Scaffold Based on Collagen I with Chitosan Micro- and nanofibres",
  annote="The aim of this study was to evaluate macroscopically,
histologically and immunohistochemically the quality of newly
formed tissue in iatrogenic defects of articular cartilage of the
femur condyle in miniature pigs treated with the clinically used
method of microfractures in comparison with the transplantation
of a combination of a composite scaffold with allogeneic
mesenchymal stem cells (MSCs) or the composite scaffold alone.",
  address="Institute of Physiology,Academy of Sciences of the Czech Republic",
  chapter="50968",
  institution="Institute of Physiology,Academy of Sciences of the Czech Republic",
  journal="Physiological Research",
  number="4",
  volume="59",
  year="2010",
  month="september",
  pages="605--614",
  publisher="Institute of Physiology,Academy of Sciences of the Czech Republic",
  type="journal article - other"
}