Publication detail

The segmentation of zones with increased autofluorescence in the junctional zone of parapapillary atrophy

KOLÁŘ, R. JAN, J. LAEMMER, R. MARDIN, C.

Original Title

The segmentation of zones with increased autofluorescence in the junctional zone of parapapillary atrophy

English Title

The segmentation of zones with increased autofluorescence in the junctional zone of parapapillary atrophy

Type

journal article - other

Language

Czech

Original Abstract

The autofluorescence (AF) derived from the retinal pigment epithelium has the potential to be used as a feature for early glaucoma diagnosis. The aim of this paper is to design and evaluate the method used for semi-automatic segmentation of the zones with increased autofluorescence. A randomized sample of 20 patients (age: 56 +/- 10 years) with open angle glaucoma was used. A new method for semi-automatic detection and segmentation of the zones with a higher level of autofluorescence in the junctional zone of parapapillary atrophy has been evaluated. Good agreement has been observed between manually and semi-automatically segmented zones for most of the images, but higher differences may occur for larger hyperfluorescent regions. The data were evaluated using the limits of agreement, with a 2*sigma border. The described method allows fast and objective evaluation of AF images, preventing undesirable inter-expert variance. A large proportion of AF images could be evaluated successfully by the developed procedure, and the obtained results are comparable to the manual procedure in most cases.

English abstract

The autofluorescence (AF) derived from the retinal pigment epithelium has the potential to be used as a feature for early glaucoma diagnosis. The aim of this paper is to design and evaluate the method used for semi-automatic segmentation of the zones with increased autofluorescence. A randomized sample of 20 patients (age: 56 +/- 10 years) with open angle glaucoma was used. A new method for semi-automatic detection and segmentation of the zones with a higher level of autofluorescence in the junctional zone of parapapillary atrophy has been evaluated. Good agreement has been observed between manually and semi-automatically segmented zones for most of the images, but higher differences may occur for larger hyperfluorescent regions. The data were evaluated using the limits of agreement, with a 2*sigma border. The described method allows fast and objective evaluation of AF images, preventing undesirable inter-expert variance. A large proportion of AF images could be evaluated successfully by the developed procedure, and the obtained results are comparable to the manual procedure in most cases.

Keywords

autofluorescence, parapapillary atrophy, glaucoma, image segmentation

Key words in English

autofluorescence, parapapillary atrophy, glaucoma, image segmentation

Authors

KOLÁŘ, R.; JAN, J.; LAEMMER, R.; MARDIN, C.

Released

1. 5. 2009

ISBN

0967-3334

Periodical

PHYSIOLOGICAL MEASUREMENT

Year of study

2009

Number

30

State

United Kingdom of Great Britain and Northern Ireland

Pages from

505

Pages to

516

Pages count

11

URL

https://iopscience.iop.org/article/10.1088/0967-3334/30/5/007

BibTex

@article{BUT48070,
  author="Radim {Kolář} and Jiří {Jan} and Robert {Laemmer} and Christian Y {Mardin}",
  title="The segmentation of zones with increased autofluorescence in the junctional zone of parapapillary atrophy",
  journal="PHYSIOLOGICAL MEASUREMENT",
  year="2009",
  volume="2009",
  number="30",
  pages="505--516",
  issn="0967-3334",
  url="https://iopscience.iop.org/article/10.1088/0967-3334/30/5/007"
}