Publication detail

COMPUTATIONAL MODELLING OF BEHAVIOUR OF SOFT BIOLOGICAL TISSUES

BURŠA, J., LEBIŠ, R., RYŠAVÝ, P.

Original Title

COMPUTATIONAL MODELLING OF BEHAVIOUR OF SOFT BIOLOGICAL TISSUES

English Title

COMPUTATIONAL MODELLING OF BEHAVIOUR OF SOFT BIOLOGICAL TISSUES

Type

conference paper

Language

en

Original Abstract

Abstract: The paper deals with computational modelling of mechanical behaviour of soft tissues in arterial wall. Three computational models are presented. Model No. 1 models abdominal aortic aneurysms (AAA) at the level of a multilayer aortic wall structure with hyperelastic isotropic material properties of the individual layers. The extreme principal stress in the AAA is evaluated and compared with the stress in an intact aorta. The ratio of these stresses should be used in the evaluation of AAA rupture risk. Model No. 2 models an individual smooth muscle cell (SMC) at the level of a homogeneous hyperelastic isotropic continuum. Parameters of the 5-parameter-Mooney-Rivlin constitutive model are identified from the tension test of the SMC. Model No.3 models tension and indentation tests of SMCs with taking the cell structure into account, with cytoskeleton represented by a simple tensegrity structure.

English abstract

Abstract: The paper deals with computational modelling of mechanical behaviour of soft tissues in arterial wall. Three computational models are presented. Model No. 1 models abdominal aortic aneurysms (AAA) at the level of a multilayer aortic wall structure with hyperelastic isotropic material properties of the individual layers. The extreme principal stress in the AAA is evaluated and compared with the stress in an intact aorta. The ratio of these stresses should be used in the evaluation of AAA rupture risk. Model No. 2 models an individual smooth muscle cell (SMC) at the level of a homogeneous hyperelastic isotropic continuum. Parameters of the 5-parameter-Mooney-Rivlin constitutive model are identified from the tension test of the SMC. Model No.3 models tension and indentation tests of SMCs with taking the cell structure into account, with cytoskeleton represented by a simple tensegrity structure.

Keywords

Computational modelling, smooth muscle cell

RIV year

2005

Released

20.11.2005

Location

Prague

Pages from

1538

Pages to

1543

Pages count

6

Documents

BibTex


@inproceedings{BUT18362,
  author="Jiří {Burša} and Radek {Lebiš} and Pavel {Ryšavý}",
  title="COMPUTATIONAL MODELLING OF BEHAVIOUR OF SOFT BIOLOGICAL TISSUES",
  annote="Abstract: The paper deals with computational modelling of mechanical behaviour of soft tissues in arterial wall. Three computational models are presented. Model No. 1 models abdominal aortic aneurysms (AAA) at the level of a multilayer aortic wall structure with hyperelastic isotropic material properties of the individual layers. The extreme principal stress in the AAA is evaluated and compared with the stress in an intact aorta. The ratio of these stresses should be used in the evaluation of AAA rupture risk. Model No. 2 models an individual smooth muscle cell (SMC) at the level of a homogeneous hyperelastic isotropic continuum. Parameters of the 5-parameter-Mooney-Rivlin constitutive model are identified from the tension test of the SMC. Model No.3 models tension and indentation tests of SMCs with taking the cell structure into account, with cytoskeleton represented by a simple tensegrity structure. 
",
  booktitle="IFMBE Proceedings",
  chapter="18362",
  journal="IFMBE Proceedings",
  number="11",
  year="2005",
  month="november",
  pages="1538",
  type="conference paper"
}