Publication detail

Maghemite particles for spermidine separation

KOPEL, P. CERNEI, N. HORKÝ, P. LACKOVÁ, Z. MILOSAVLJEVIĆ, V. GAGIĆ, M. ZÍTKA, O. ADAM, V.

Original Title

Maghemite particles for spermidine separation

Type

conference paper

Language

English

Original Abstract

We report the optimal conditions for the separation of spermidine from different types of samples, for example blood or cancer cells and its subsequent determination by ion-exchange liquid chromatography (IEC) with UV-VIS detector. Here in, we synthesized paramagnetic particles able to isolate and immobilize spermidine from blood of patients with cancer or cancer cells and thus preconcentrate it for analysis. Dowex surface was covered by nanomaghemite (γ-Fe2O3) or maghemite particles surface was modified by chitosan and sulfoxyethyl cellulose. The best separation properties showed Dowex microparticles. The paramagnetic particles can be used in the future for isolation of spermidine from real samples and diagnosis of cancer.

Keywords

Ion exchange chromatography; maghemite; spermidine; chitosan and sulfoxyethyl cellulose

Authors

KOPEL, P.; CERNEI, N.; HORKÝ, P.; LACKOVÁ, Z.; MILOSAVLJEVIĆ, V.; GAGIĆ, M.; ZÍTKA, O.; ADAM, V.

Released

10. 6. 2020

Publisher

Tanger

ISBN

978-80-87294-95-6

Book

NANOCON 2019 CONFERENCE PROCEEDINGS

Edition

1.

Pages from

353

Pages to

357

Pages count

5

URL

https://doi.org/10.37904/nanocon.2019.8496

Full text in the Digital Library

http://hdl.handle.net/11012/196671

BibTex

@inproceedings{BUT164258,
  author="Pavel {Kopel} and Natalia Vladimirovna {Cernei} and Pavel {Horký} and Zuzana {Lacková} and Vedran {Milosavljević} and Milica {Gagić} and Ondřej {Zítka} and Vojtěch {Adam}",
  title="Maghemite particles for spermidine separation",
  booktitle="NANOCON 2019 CONFERENCE PROCEEDINGS",
  year="2020",
  series="1.",
  pages="353--357",
  publisher="Tanger",
  doi="10.37904/nanocon.2019.8496",
  isbn="978-80-87294-95-6",
  url="https://doi.org/10.37904/nanocon.2019.8496"
}