Publication detail

Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic)

KALOVÁ, K. BOBEROVÁ, K. PŘICHYSTALOVÁ, R. NOVÁČEK, J. JAROŠOVÁ, I. ZIKMUND, T. KAISER, J. KYSELICOVÁ, K. ŠEBEST, L. BALDOVIČ, M. FRTÚS, A. SIKORA, M. ALLENTOFT, M.

Original Title

Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic)

Type

journal article in Web of Science

Language

English

Original Abstract

The skeletal remains of the young female (20-24 years) from Grave JP/106, discovered in the Southern Suburb of the Breclav - Pohansko Stronghold (Early Middle Ages, 9th century-beginning of the 10th century, present day Czech Republic) display several noteworthy pathologies. The first is deformation of the mandible, which was most probably caused by a fracture of the ramus in combination with a subcondylar fracture. The spine of this young woman also exhibits a probable traumatic injury of the cervical spine in combination with a slowly growing structure situated inside the spinal canal, which caused deformation centered upon C7. The cervical and thoracic spine together with internal surfaces of several ribs exhibit infectious changes of advanced stage, in all likelihood of tuberculous origin, but osteomyelitis cannot be excluded. Histological analysis of the new bone formation in the ribs confirmed infectious origin, as does Micro CT of C5 and C6. Analyses conducted by two different departments with different methods (PCR amplification of 123 bp long section from IS6110 and Next Generation shotgun sequencing) failed to identify DNA of Mycobacterium tuberculosis from the first rib.

Keywords

Palaeopathology; Tuberculosis; Osteomyelitis; Mycosis; Trauma; Fracture; Pohansko; Early middle ages

Authors

KALOVÁ, K.; BOBEROVÁ, K.; PŘICHYSTALOVÁ, R.; NOVÁČEK, J.; JAROŠOVÁ, I.; ZIKMUND, T.; KAISER, J.; KYSELICOVÁ, K.; ŠEBEST, L.; BALDOVIČ, M.; FRTÚS, A.; SIKORA, M.; ALLENTOFT, M.

Released

1. 3. 2019

ISBN

1879-9817

Periodical

International Journal of Paleopathology

Year of study

24

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

185

Pages to

196

Pages count

12

URL

https://www.sciencedirect.com/science/article/pii/S1879981717301559?via%3Dihub

BibTex

@article{BUT157482,
  author="Kateřina {Kalová} and Kateřina {Boberová} and Renáta {Přichystalová} and Jan {Nováček} and Ivana {Jarošová} and Tomáš {Zikmund} and Jozef {Kaiser} and Klaudia {Kyselicová} and Lukáš {Šebest} and Marián {Baldovič} and Adam {Frtús} and Martin {Sikora} and Morten Eric {Allentoft}",
  title="Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic)",
  journal="International Journal of Paleopathology",
  year="2019",
  volume="24",
  number="1",
  pages="185--196",
  doi="10.1016/j.ijpp.2018.11.004",
  issn="1879-9817",
  url="https://www.sciencedirect.com/science/article/pii/S1879981717301559?via%3Dihub"
}