Publication detail

In vivo biocompatibility of site-directed apoferritin-based nanocarrier for cardiotoxic antitumour drug doxorubicin

DOSTÁLOVÁ, S. POLANSKÁ, H. SVOBODOVÁ, M. BALVAN, J. KRYŠTOFOVÁ, O. MASAŘÍK, M. ECKSCHLAGER, T. STIBOROVÁ, M. HEGER, Z. ADAM, V.

Original Title

In vivo biocompatibility of site-directed apoferritin-based nanocarrier for cardiotoxic antitumour drug doxorubicin

Type

conference paper

Language

English

Original Abstract

Doxorubicin (DOX), a potent anthracycline antibiotic [1], is used in conventional cancer therapy for the treatment of various solid and haematological malignancies, such as breast [2], lung [3], bladder [4] or Hodgkin lymphoma [5]. However, up to 26% of patients treated with DOX develop arrhythmia or cardiomyopathy [6]. Co-administration with cardioprotective drugs can lead to other unwanted side effects, such as the development of secondary malignancies in case of dexrazoxane [7]. This effectively limits DOX dose that can be administered to the patients [6].

Keywords

Doxorubicin (DOX); cancer cells; nanocarrier

Authors

DOSTÁLOVÁ, S.; POLANSKÁ, H.; SVOBODOVÁ, M.; BALVAN, J.; KRYŠTOFOVÁ, O.; MASAŘÍK, M.; ECKSCHLAGER, T.; STIBOROVÁ, M.; HEGER, Z.; ADAM, V.

Released

10. 5. 2017

ISBN

2296-9667

Periodical

European & Global Summit for Clinical Nanomedicine and Targeted Medicine

State

Swiss Confederation

Pages from

168

Pages to

169

Pages count

2

BibTex

@inproceedings{BUT141783,
  author="Simona {Dostálová} and Hana {Polanská} and Markéta {Svobodová} and Jan {Balvan} and Olga {Kryštofová} and Michal {Masařík} and Tomáš {Eckschlager} and Marie {Stiborová} and Zbyněk {Heger} and Vojtěch {Adam}",
  title="In vivo biocompatibility of site-directed apoferritin-based nanocarrier for cardiotoxic antitumour drug doxorubicin",
  booktitle="10th European and Global Summit for Clinical Nanomedicine and Targeted Medicine: witnessing the solutions and tackling the hurdles",
  year="2017",
  journal="European & Global Summit for Clinical Nanomedicine and Targeted Medicine",
  pages="168--169",
  issn="2296-9667"
}