Publication detail

Tensigrity Principle Based Computational Model of Cytoskeleton.

BANSOD, Y. BURŠA, J.

Original Title

Tensigrity Principle Based Computational Model of Cytoskeleton.

Type

conference paper

Language

English

Original Abstract

The cytoskeleton plays a vital role in intracellular transmission of mechanical signals. The computational model of cytoskeleton based on tensegrity principle presented here has tension supporting cables representing microfilaments, compression supporting struts representing microtubules and springs in tension representing intermediate filaments. The nucleoskeleton and centrosome modelled as self-stabilised regular truncated tensegrity structures aimed to withstand high prestress. Integrins connecting cell with extracellular matrix are also considered to define cell behaviour in vivo. In this way, a more realistic computational model of cytoskeleton for different cell types could be designed for better understanding of respective cell motility and intracellular transmission of mechanical signals.

Keywords

Cell mechanics, computational models, Tensegrity, Cytoskeleton

Authors

BANSOD, Y.; BURŠA, J.

RIV year

2014

Released

15. 7. 2014

Publisher

6th World Conference on Structural Control and Monitoring (6WCSCM).

Location

Barcelona, Spain

ISBN

978-84-942844-5-8

Book

6th World Conference on Structural Control and Monitoring (6WCSCM)

Pages from

3317

Pages to

3326

Pages count

10

BibTex

@inproceedings{BUT116147,
  author="Yogesh Deepak {Bansod} and Jiří {Burša}",
  title="Tensigrity Principle Based Computational Model of Cytoskeleton.",
  booktitle="6th World Conference on Structural Control and Monitoring (6WCSCM)",
  year="2014",
  pages="3317--3326",
  publisher="6th World Conference on Structural Control and Monitoring (6WCSCM).",
  address="Barcelona, Spain",
  isbn="978-84-942844-5-8"
}