Publication detail

Computational Model of Cytoskeleton Based on Tensegrity Principle

BANSOD, Y. BURŠA, J.

Original Title

Computational Model of Cytoskeleton Based on Tensegrity Principle

English Title

Computational Model of Cytoskeleton Based on Tensegrity Principle

Type

abstract

Language

en

Original Abstract

Ingber proposed tensegrity model for cytoskeleton which viewed actin filaments as tension supporting cables and microtubules as compression-supporting struts. In present model the tensed membrane skeleton is constructed out of polyhedron and consists of cross-linked microfilaments only. Microtubules, modelled as discrete compression members, emerge from centrosome, have unequal lengths and form a star shape. Intermediate filaments are modelled as springs in tension, tangential to nucleoskeleton and spread throughout intracellular region. In this way various more realistic computational cellular tensegrity models could be designed for better understanding of cellular mechanics.

English abstract

Ingber proposed tensegrity model for cytoskeleton which viewed actin filaments as tension supporting cables and microtubules as compression-supporting struts. In present model the tensed membrane skeleton is constructed out of polyhedron and consists of cross-linked microfilaments only. Microtubules, modelled as discrete compression members, emerge from centrosome, have unequal lengths and form a star shape. Intermediate filaments are modelled as springs in tension, tangential to nucleoskeleton and spread throughout intracellular region. In this way various more realistic computational cellular tensegrity models could be designed for better understanding of cellular mechanics.

Keywords

Cell mechanics, computational models, Tensegrity

Released

21.05.2014

Publisher

XXII Cytoskeletal Club, Veterinary Research Institute, Masaryk University.

Location

Vranovska Ves, Czech Republic.

Documents

BibTex


@misc{BUT116086,
  author="Yogesh Deepak {Bansod} and Jiří {Burša}",
  title="Computational Model of Cytoskeleton Based on Tensegrity Principle",
  annote="Ingber proposed tensegrity model for cytoskeleton which viewed actin filaments as tension supporting cables and microtubules as compression-supporting struts. In present model the tensed membrane skeleton is constructed out of polyhedron and consists of cross-linked microfilaments only. Microtubules, modelled as discrete compression members, emerge from centrosome, have unequal lengths and form a star shape. Intermediate filaments are modelled as springs in tension, tangential to nucleoskeleton and spread throughout intracellular region. In this way various more realistic computational cellular tensegrity models could be designed for better understanding of cellular mechanics.",
  address="XXII Cytoskeletal Club, Veterinary Research Institute, Masaryk University.",
  chapter="116086",
  howpublished="online",
  institution="XXII Cytoskeletal Club, Veterinary Research Institute, Masaryk University.",
  year="2014",
  month="may",
  publisher="XXII Cytoskeletal Club, Veterinary Research Institute, Masaryk University.",
  type="abstract"
}