Publication detail

The influence of ionic strength on aggregation of mixed liposomal system with polyelectrolyte

SZEWIECZKOVÁ, J. MRAVEC, F. PEKAŘ, M.

Original Title

The influence of ionic strength on aggregation of mixed liposomal system with polyelectrolyte

English Title

The influence of ionic strength on aggregation of mixed liposomal system with polyelectrolyte

Type

abstract

Language

en

Original Abstract

By mixing of biocompatible zwitterionic phospholipid with cationic lipid we get composite structures with improved mechanical stability which could be utilized in interactions with polyelectrolyte. This work is based on studying of formation of mixed liposomal systems and of interactions of these mixed systems with hyaluronic acid in water and physiological solution. Systems were studied using fluorescence spectroscopy. Pyrene was utilized as a fluorescence probe because of its sensitivity to polarity of the local environment.

English abstract

By mixing of biocompatible zwitterionic phospholipid with cationic lipid we get composite structures with improved mechanical stability which could be utilized in interactions with polyelectrolyte. This work is based on studying of formation of mixed liposomal systems and of interactions of these mixed systems with hyaluronic acid in water and physiological solution. Systems were studied using fluorescence spectroscopy. Pyrene was utilized as a fluorescence probe because of its sensitivity to polarity of the local environment.

Keywords

Lipid, liposome, , hyaluronan, pyrene.

Released

23.04.2015

Publisher

Masarykova Univerzita

Location

Brno

ISBN

978-80-210-7825-3

Book

CEITEC PHD RETREAT

Edition

first

Pages from

122

Pages to

122

Pages count

1

BibTex


@misc{BUT114355,
  author="Jana {Burdíková} and Filip {Mravec} and Miloslav {Pekař}",
  title="The influence of ionic strength on aggregation of mixed liposomal system with polyelectrolyte",
  annote="By mixing of biocompatible zwitterionic phospholipid with cationic lipid we get composite structures with improved mechanical stability which could be utilized in interactions with polyelectrolyte. This work is based on studying of formation of mixed liposomal systems and of interactions of these mixed systems with hyaluronic acid in water and physiological solution. Systems were studied using fluorescence spectroscopy. Pyrene was utilized as a fluorescence probe because of its sensitivity to polarity of the local environment.",
  address="Masarykova Univerzita",
  booktitle="CEITEC PHD RETREAT",
  chapter="114355",
  edition="first",
  howpublished="print",
  institution="Masarykova Univerzita",
  year="2015",
  month="april",
  pages="122--122",
  publisher="Masarykova Univerzita",
  type="abstract"
}