Publication detail

Crosslinked Polyurethane Elastomers Based on Bioresorbable Polyols with Potential Use in Medicine

KUPKA, V. VOJTOVÁ, L. JANČÁŘ, J.

Original Title

Crosslinked Polyurethane Elastomers Based on Bioresorbable Polyols with Potential Use in Medicine

English Title

Crosslinked Polyurethane Elastomers Based on Bioresorbable Polyols with Potential Use in Medicine

Type

abstract

Language

en

Original Abstract

Biodegradable polyurethane (bio-PU) elastomers with potential use as artificial veins in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate catalyzed with tin-2-ethyl hexanoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 7:3, 1:1 and 3:7 were used. Samples made of one type of diol, either hydrophilic PEG or hy-drophobic PCL, were synthesized as well. Subsequently samples made of PEG/PCL in ratios 2:8 and 1:9 were synthesized also to tune the mechanical properties. Influence of the composition on the structure is discussed in this contribution.

English abstract

Biodegradable polyurethane (bio-PU) elastomers with potential use as artificial veins in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate catalyzed with tin-2-ethyl hexanoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 7:3, 1:1 and 3:7 were used. Samples made of one type of diol, either hydrophilic PEG or hy-drophobic PCL, were synthesized as well. Subsequently samples made of PEG/PCL in ratios 2:8 and 1:9 were synthesized also to tune the mechanical properties. Influence of the composition on the structure is discussed in this contribution.

Keywords

polyurethane, elastomer, biodegradable, poly(ethylene glycol), poly(caprolactone)

Released

22.08.2014

Location

Maďarsko, konference BiPoCo

BibTex


@misc{BUT111985,
  author="Vojtěch {Kupka} and Lucy {Vojtová} and Josef {Jančář}",
  title="Crosslinked Polyurethane Elastomers Based on Bioresorbable Polyols with Potential Use in Medicine",
  annote="Biodegradable polyurethane (bio-PU) elastomers with potential use as artificial veins in regenerative medicine were synthesized by solvent free method using poly(ethylene glycol) (PEG), poly(caprolactone) (PCL) and hexamethylene diisocyanate catalyzed with tin-2-ethyl hexanoate. Different diol hydrophilic (PEG) to hydrophobic (PCL) content ratios of 7:3, 1:1 and 3:7 were used. Samples made of one type of diol, either hydrophilic PEG or hy-drophobic PCL, were synthesized as well. Subsequently samples made of PEG/PCL in ratios 2:8 and 1:9 were synthesized also to tune the mechanical properties. Influence of the composition on the structure is discussed in this contribution.",
  chapter="111985",
  year="2014",
  month="august",
  type="abstract"
}