Publication detail

Semi-automatic motion compensation of contrast-enhanced ultrasound images from abdominal organs for perfusion analysis

SCHÄFER, S. NYLUND, K. SAVIK, F. ENGJOM, T. MÉZL, M. JIŘÍK, R. DIMCEVSKI, G. GILJA, O. TÖNNIES, K.

Original Title

Semi-automatic motion compensation of contrast-enhanced ultrasound images from abdominal organs for perfusion analysis

Type

journal article in Web of Science

Language

English

Original Abstract

This paper presents a system for correcting motion influences in time-dependent 2D contrast-enhanced ultrasound (CEUS) images to assess tissue perfusion characteristics. The system consists of a semi-automatic frame selection method to find images with out-of-plane motion as well as a method for automatic motion compensation. Translational and non-rigid motion compensation is applied by introducing a temporal continuity assumption. A study consisting of 40 clinical datasets was conducted to compare the perfusion with simulated perfusion using pharmacokinetic modeling. Overall, the proposed approach decreased the mean average difference between the measured perfusion and the pharmacokinetic model estimation. It was non-inferior for three out of four patient cohorts to a manual approach and reduced the analysis time by 41% compared to manual processing.

Keywords

Ultrasonography, Motion analysis, Motion compensation, Registration, CEUS, Contrast-enhanced ultrasound, Perfusion, Perfusion modeling

Authors

SCHÄFER, S.; NYLUND, K.; SAVIK, F.; ENGJOM, T.; MÉZL, M.; JIŘÍK, R.; DIMCEVSKI, G.; GILJA, O.; TÖNNIES, K.

RIV year

2015

Released

16. 10. 2014

Publisher

Elsevier

ISBN

0010-4825

Periodical

COMPUTERS IN BIOLOGY AND MEDICINE

Year of study

-

Number

-

State

United States of America

Pages from

1

Pages to

9

Pages count

9

URL

http://www.sciencedirect.com/science/article/pii/S0010482514002716

BibTex

@article{BUT110377,
  author="Sebastian {Schäfer} and Kim {Nylund} and Fredrik {Sævik} and Trond {Engjom} and Martin {Mézl} and Radovan {Jiřík} and Georg {Dimcevski} and Odd Helge {Gilja} and Klaus {Tönnies}",
  title="Semi-automatic motion compensation of contrast-enhanced ultrasound images from abdominal organs for perfusion analysis",
  journal="COMPUTERS IN BIOLOGY AND MEDICINE",
  year="2014",
  volume="-",
  number="-",
  pages="1--9",
  doi="10.1016/j.compbiomed.2014.09.014",
  issn="0010-4825",
  url="http://www.sciencedirect.com/science/article/pii/S0010482514002716"
}