Publication detail

Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis

VOGEL, I. OČENÁŠEK, P. ZEDEK, F.

Original Title

Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis

English Title

Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis

Type

conference paper

Language

en

Original Abstract

In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project.

English abstract

In the proposed paper we analyse and discuss the molecular evolution from the point of view of mathematical analysis and statistics. Some characteristics of distance-based algorithms for phylogenetic inference are depicted. We furthermore use knowledge of mathematical models to design a modified algorithm for phylogenetic tree reconstruction. We implement the presented methods in the form of a simple phylogenetic library, briefly report about results of our case study and finally show a way for building a web interface for biological purposes through Mobyle portal. Finally, we draw a conclusion and discuss possible future work on the project.

Keywords

phylogeny, intra-group analysis, substitution model, Markov chains

RIV year

2011

Released

05.04.2011

Publisher

Brno University of Technology

Location

Brno

ISBN

978-80-214-4303-7

Book

EDS '11 IMAPS CS International Conference Proceedings

Edition

NEUVEDEN

Edition number

NEUVEDEN

Pages from

264

Pages to

269

Pages count

6

BibTex


@inproceedings{BUT76292,
  author="Ivan {Vogel} and Pavel {Očenášek} and František {Zedek}",
  title="Computational molecular evolution - from mathematical models to novel distance metric based on intra-group analysis",
  annote="In the proposed paper we analyse and discuss the molecular evolution from the
point of view of mathematical analysis and statistics. Some characteristics of
distance-based algorithms for phylogenetic inference are depicted. We furthermore
use knowledge of mathematical models to design a modified algorithm for
phylogenetic tree reconstruction. We implement the presented methods in the form
of a simple phylogenetic library, briefly report about results of our case study
and finally show a way for building a web interface for biological purposes
through Mobyle portal. Finally, we draw a conclusion and discuss possible future
work on the project.",
  address="Brno University of Technology",
  booktitle="EDS '11 IMAPS CS International Conference Proceedings",
  chapter="76292",
  edition="NEUVEDEN",
  howpublished="print",
  institution="Brno University of Technology",
  year="2011",
  month="april",
  pages="264--269",
  publisher="Brno University of Technology",
  type="conference paper"
}