Publication detail

Electrochemical study of doxorubicin interaction with different sequences of double stranded oligonucleotides, Part II.

HYNEK, D. KREJČOVÁ, L. ZÍTKA, O. ADAM, V. TRNKOVÁ, L. SOCHOR, J. STIBOROVÁ, M. ECKSCHLAGER, T. HUBÁLEK, J. KIZEK, R.

Original Title

Electrochemical study of doxorubicin interaction with different sequences of double stranded oligonucleotides, Part II.

Type

journal article in Web of Science

Language

English

Original Abstract

Interaction of low molecular weight compounds with DNA is one of the general mechanisms used for effective anticancer therapy. Doxorubicin is one of the anthracycline drugs, which represent a mixture to that effect. This paper focuses on the study of interactions with doxorubicin dvouřetězcovými ODN (dsODN) using adsorptive transfer stripping square wave voltammetry. The identified changes are described and differences in the behavior of individual dsODNs are linked to their structure.

Keywords

intercalating drug; doxorubicin; hetero-nucleotides; square wave voltammetry; adsorptive transfer stripping technique; adriamycin; DNA

Authors

HYNEK, D.; KREJČOVÁ, L.; ZÍTKA, O.; ADAM, V.; TRNKOVÁ, L.; SOCHOR, J.; STIBOROVÁ, M.; ECKSCHLAGER, T.; HUBÁLEK, J.; KIZEK, R.

RIV year

2012

Released

1. 1. 2012

ISBN

1452-3981

Periodical

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE

Year of study

7

Number

1

State

Republic of Serbia

Pages from

34

Pages to

49

Pages count

16

BibTex

@article{BUT75711,
  author="HYNEK, D. and KREJČOVÁ, L. and ZÍTKA, O. and ADAM, V. and TRNKOVÁ, L. and SOCHOR, J. and STIBOROVÁ, M. and ECKSCHLAGER, T. and HUBÁLEK, J. and KIZEK, R.",
  title="Electrochemical study of doxorubicin interaction with different sequences of double stranded oligonucleotides, Part II.",
  journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE",
  year="2012",
  volume="7",
  number="1",
  pages="34--49",
  issn="1452-3981"
}