Publication detail

Nanocarriers for anticancer drugs - New trends in nanomedicine

DRBOHLAVOVÁ, J. CHOMOUCKÁ, J. ADAM, V. VACULOVIČOVÁ, M. HUBÁLEK, J. KIZEK, R.

Original Title

Nanocarriers for anticancer drugs - New trends in nanomedicine

Type

journal article - other

Language

English

Original Abstract

This review provides a brief overview of the variety of carriers employed for targeted drug delivery used in cancer therapy summarizing advantages and disadvantages of each approach. Particularly, we aim our attention at polymeric nanocarriers, liposomes, micelles, polyethylene glycol, poly(lactic-co-glycolic acid), dendrimers, gold and magnetic nanoparticles, quantum dots, silica nanoparticles and carbon nanotubes. Further, we briefly focus on several anticancer agents (paclitaxel, docetaxel, camptothecin, doxorubicin, daunorubicin, cisplatin, curcumin and geldanamycin) and to the influence of their combination with nanoparticulate transporters to their properties such as cytotoxicity, short life time and/or solubility

Keywords

Nanotechnologies; Nanoparticles; Gene Therapy; Anticancer drugs; Drug carriers; Cancer; Cytostatic; Targeted therapy.

Authors

DRBOHLAVOVÁ, J.; CHOMOUCKÁ, J.; ADAM, V.; VACULOVIČOVÁ, M.; HUBÁLEK, J.; KIZEK, R.

RIV year

2013

Released

13. 5. 2013

Publisher

Bentham Science

Location

Sharjah, U. A. E.

ISBN

1389-2002

Periodical

CURRENT DRUG METABOLISM

Year of study

14

Number

5

State

United Arab Emirates

Pages from

547

Pages to

564

Pages count

18

BibTex

@article{BUT75687,
  author="Jana {Drbohlavová} and Jana {Pekárková} and Vojtěch {Adam} and Markéta {Vaculovičová} and Jaromír {Hubálek} and René {Kizek}",
  title="Nanocarriers for anticancer drugs - New trends in nanomedicine",
  journal="CURRENT DRUG METABOLISM",
  year="2013",
  volume="14",
  number="5",
  pages="547--564",
  doi="10.2174/1389200211314050005",
  issn="1389-2002"
}