Publication detail

Effects of Voltage-Sensitive Dye di-4-ANEPPS on Isolated Rat Heart Electrogram

FIALOVÁ, K. KOLÁŘOVÁ, J. JANOUŠEK, O. RONZHINA, M. PROVAZNÍK, I. NOVÁKOVÁ, M.

Original Title

Effects of Voltage-Sensitive Dye di-4-ANEPPS on Isolated Rat Heart Electrogram

Czech Title

Vliv napěťově citlivého barviva di-4-ANEPPS na elektrogram izolovaného srdce potkana

English Title

Effects of Voltage-Sensitive Dye di-4-ANEPPS on Isolated Rat Heart Electrogram

Type

conference paper

Language

en

Original Abstract

Mapping of cardiac electrical activity from Langendorff-perfused hearts using the voltage-sensitive dye (VSD) di-4-ANEPPS has yielded important new information. However, data about response of the heart to staining with VSD are scarce. Voltage-sensitive dye di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials by optical method in isolated hearts. The most often used species in basic cardiology is the rat heart. In order to describe in more detail the response of the heart tissue exposed to di-4-ANEPPS, heart rate changes and arrhythmia-preceding parameters in isolated rat heart electrogram during staining with di-4-ANEPPS and washout period, were followed.

Czech abstract

Mapping of cardiac electrical activity from Langendorff-perfused hearts using the voltage-sensitive dye (VSD) di-4-ANEPPS has yielded important new information. However, data about response of the heart to staining with VSD are scarce. Voltage-sensitive dye di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials by optical method in isolated hearts. The most often used species in basic cardiology is the rat heart. In order to describe in more detail the response of the heart tissue exposed to di-4-ANEPPS, heart rate changes and arrhythmia-preceding parameters in isolated rat heart electrogram during staining with di-4-ANEPPS and washout period, were followed.

English abstract

Mapping of cardiac electrical activity from Langendorff-perfused hearts using the voltage-sensitive dye (VSD) di-4-ANEPPS has yielded important new information. However, data about response of the heart to staining with VSD are scarce. Voltage-sensitive dye di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials by optical method in isolated hearts. The most often used species in basic cardiology is the rat heart. In order to describe in more detail the response of the heart tissue exposed to di-4-ANEPPS, heart rate changes and arrhythmia-preceding parameters in isolated rat heart electrogram during staining with di-4-ANEPPS and washout period, were followed.

Keywords

di-4-ANEPPS, isolated heart, rat, electrogram

RIV year

2011

Released

20.10.2011

ISBN

978-1-4577-0612-7

Book

Computers in Cardiology

Pages from

1

Pages to

4

Pages count

4

BibTex


@inproceedings{BUT74001,
  author="Kateřina {Fialová} and Jana {Kolářová} and Oto {Janoušek} and Marina {Ronzhina} and Ivo {Provazník} and Marie {Nováková}",
  title="Effects of Voltage-Sensitive Dye di-4-ANEPPS on Isolated Rat Heart Electrogram",
  annote="Mapping of cardiac electrical activity from Langendorff-perfused hearts using the voltage-sensitive dye (VSD) di-4-ANEPPS has yielded important new information. However, data about response of the heart to staining with VSD are scarce. Voltage-sensitive dye di-4-ANEPPS is currently used in our laboratory for recording of monophasic action potentials by optical method in isolated hearts. The most often used species in basic cardiology is the rat heart. In order to describe in more detail the response of the heart tissue exposed to di-4-ANEPPS, heart rate changes and arrhythmia-preceding parameters in isolated rat heart electrogram during staining with di-4-ANEPPS and washout period, were followed.",
  booktitle="Computers in Cardiology",
  chapter="74001",
  howpublished="electronic, physical medium",
  year="2011",
  month="october",
  pages="1--4",
  type="conference paper"
}