Publication detail
MY_UMI_TOOL: Processing of Unique Molecular Identifiers without Mapping to a Reference Genome
BARILÍKOVÁ, L.
Original Title
MY_UMI_TOOL: Processing of Unique Molecular Identifiers without Mapping to a Reference Genome
English Title
MY_UMI_TOOL: Processing of Unique Molecular Identifiers without Mapping to a Reference Genome
Type
conference paper
Language
en
Original Abstract
The presented paper describes a novel algorithm for processing unique molecular identifiers (UMIs) without mapping to a reference genome. For the past few years, there has been a rapid rise in the use of sequencing technologies and progress in bioinformatics tools. However, available tools for processing UMIs are usually relative computationally demanding and time-consuming which led us to design and develop a new algorithm as well as to implement some available software to provide an effective estimation of the total number of unique molecules. My_UMI_tool performs four major steps: preprocessing of an input file, clustering by UMIs, clustering by sequence similarity, and marking duplicates to generate final file.
English abstract
The presented paper describes a novel algorithm for processing unique molecular identifiers (UMIs) without mapping to a reference genome. For the past few years, there has been a rapid rise in the use of sequencing technologies and progress in bioinformatics tools. However, available tools for processing UMIs are usually relative computationally demanding and time-consuming which led us to design and develop a new algorithm as well as to implement some available software to provide an effective estimation of the total number of unique molecules. My_UMI_tool performs four major steps: preprocessing of an input file, clustering by UMIs, clustering by sequence similarity, and marking duplicates to generate final file.
Keywords
unique molecular identifiers (UMIs); next-generation sequencing (NGS); PCR error
Released
23.04.2020
Publisher
Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií
Location
Brno
ISBN
978-80-214-5868-0
Book
PROCEEDINGS II OF THE 26TH CONFERENCE STUDENT EEICT 2020
Edition number
1
Pages from
76
Pages to
79
Pages count
4
URL
Documents
BibTex
@inproceedings{BUT167748,
author="Lujza {Barilíková}",
title="MY_UMI_TOOL: Processing of Unique Molecular Identifiers without Mapping to a Reference Genome",
annote="The presented paper describes a novel algorithm for processing unique molecular identifiers (UMIs) without mapping to a reference genome. For the past few years, there has been a rapid rise in the use of sequencing technologies and progress in bioinformatics tools. However, available tools for processing UMIs are usually relative computationally demanding and time-consuming which led us to design and develop a new algorithm as well as to implement some available software to provide an effective estimation of the total number of unique molecules. My_UMI_tool performs four major steps: preprocessing of an input file, clustering by UMIs, clustering by sequence similarity, and marking duplicates to generate final file.",
address="Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií",
booktitle="PROCEEDINGS II OF THE 26TH CONFERENCE STUDENT EEICT 2020",
chapter="167748",
howpublished="online",
institution="Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií",
year="2020",
month="april",
pages="76--79",
publisher="Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií",
type="conference paper"
}