Publication detail

Atmospheric Pressure Plasma Polymerized 2-Ethyl-2-oxazoline Based Thin Films for Biomedical Purposes

MAZÁNKOVÁ, V. SŤAHEL, P. MATOUŠKOVÁ, P. BRABLEC, A. ČECH, J. PROKEŠ, L. BURŠÍKOVÁ, V. STUPAVSKÁ, M. LEHOCKÝ, M. OZALTIN, K. HUMPOLÍČEK, P. TRUNEC, D.

Original Title

Atmospheric Pressure Plasma Polymerized 2-Ethyl-2-oxazoline Based Thin Films for Biomedical Purposes

Type

journal article in Web of Science

Language

English

Original Abstract

Polyoxazoline thin coatings were deposited on glass substrates using atmospheric pressure plasma polymerization from 2-ethyl-2-oxazoline vapours. The plasma polymerization was performed in dielectric barrier discharge burning in nitrogen at atmospheric pressure. The thin films stable in aqueous environments were obtained at the deposition with increased substrate temperature, which was changed from 20 degrees C to 150 degrees C. The thin film deposited samples were highly active against both S. aureus and E. coli strains in general. The chemical composition of polyoxazoline films was studied by FTIR and XPS, the mechanical properties of films were studied by depth sensing indentation technique and by scratch tests. The film surface properties were studied by AFM and by surface energy measurement. After tuning the deposition parameters (i.e., monomer flow rate and substrate temperature), stable films, which resist bacterial biofilm formation and have cell-repellent properties, were achieved. Such antibiofouling polyoxazoline thin films can have many potential biomedical applications.

Keywords

antibiofouling; plasma polymer; oxazoline

Authors

MAZÁNKOVÁ, V.; SŤAHEL, P.; MATOUŠKOVÁ, P.; BRABLEC, A.; ČECH, J.; PROKEŠ, L.; BURŠÍKOVÁ, V.; STUPAVSKÁ, M.; LEHOCKÝ, M.; OZALTIN, K.; HUMPOLÍČEK, P.; TRUNEC, D.

Released

13. 11. 2020

Publisher

MDPI

Location

BASEL

ISBN

2073-4360

Periodical

Polymers

Year of study

12

Number

11

State

Swiss Confederation

Pages from

1

Pages to

15

Pages count

15

URL

Full text in the Digital Library

BibTex

@article{BUT167298,
  author="Věra {Mazánková} and Pavel {Sťahel} and Petra {Skoumalová} and Antonín {Brablec} and Jan {Čech} and Lubomír {Prokeš} and Vilma {Buršíková} and Monika {Stupavská} and Marián {Lehocký} and Kadir {Ozaltin} and Petr {Humpolíček} and David {Trunec}",
  title="Atmospheric Pressure Plasma Polymerized 2-Ethyl-2-oxazoline Based Thin Films for Biomedical Purposes",
  journal="Polymers",
  year="2020",
  volume="12",
  number="11",
  pages="1--15",
  doi="10.3390/polym12112679",
  issn="2073-4360",
  url="https://www.mdpi.com/2073-4360/12/11/2679"
}