Measurement of blood filling in lower limbs by bioimpedance method

journal article in Web of Science

English

Background: Cardiovascular diseases are the leading causes of mortality and morbidity in modern society. The autonomic nervous systems innervate blood vessel walls and regulate contraction and wall tension. The head-up tilt test is frequently performed for evaluating sympathetic nervous system function. The filling of the lower extremities during the head-up tilt test is measured by the bioimpedance method. Increased blood volume in the area of interest increases the electrical impedance of this area. Methods: We used a mathematical fitting model to express the measured data. A B time constant of a decreased bioimpedance signal during a head-up tilt was calculated for the right leg during various time intervals of tilt duration. We optimized the duration in a study protocol based on corresponding measured data and a calculated model. A group of 22 healthy volunteers (11 men and 11 women) participated in the study protocol: the protocol included a 2-minute supine position and 5-minute head-up tilt test. Results: According to the Mann-Whitney test, there were no statistical differences in the B constant between the groups of men and women. Our results showed the optimal time duration of the head-up tilt test to be about 270 s. Conclusions: Calculating the time constant for decreased bioimpedance during a head-up tilt test might lead to a simple pre-diagnostic method for performing a non-invasive evaluation of the cardiovascular system.

bioimpedance; optimization; hemodynamics; tilt test

MATEJKOVÁ, M.; SOUKUP, L.; VONDRA, V.

6. 12. 2017

PALACKY UNIV, MEDICAL FAC, CENTRAL LIBRARY, HNEVOTINSKA 3, OLOMOUC, 00000, CZECH REPUBLIC

Olomouc

1804-7521

BIOMEDICAL PAPERS-OLOMOUC

161

Czech Republic

S15

S19

5

https://biomed.papers.upol.cz/pdfs/dou/9900/00/500.pdf