Publication detail

Application of molecularly imprinted polymers as artificial receptors for imaging

VANĚČKOVÁ, T. BEZDĚKOVÁ, J. HAN, G. ADAM, V. VACULOVIČOVÁ, M.

Original Title

Application of molecularly imprinted polymers as artificial receptors for imaging

Type

journal article in Web of Science

Language

English

Original Abstract

Medical diagnostics aims at specific localization of molecular targets as well as detection of abnormalities associated with numerous diseases. Molecularly imprinted polymers (MIPs) represent an approach of creating a synthetic material exhibiting selective recognition properties toward the desired template. The fabricated target-specific MIPs are usually well reproducible, economically efficient, and stable under critical conditions as compared to routinely used biorecognition elements such as fluorescent proteins, antibodies, enzymes, or aptamers and can even be created to those targets for which no antibodies are available. In this review, we summarize the methods of polymer fabrication. Further, we provide key for selection of the core material with imaging function depending on the imaging modality used. Finally, MIP-based imaging applications are highlighted and presented in a comprehensive form from different aspects.

Keywords

Luminescence; Polymerization; Microscopy; Affinity

Authors

VANĚČKOVÁ, T.; BEZDĚKOVÁ, J.; HAN, G.; ADAM, V.; VACULOVIČOVÁ, M.

Released

1. 1. 2020

ISBN

1742-7061

Periodical

Acta Biomaterialia

Year of study

101

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

444

Pages to

458

Pages count

15

URL

https://www.sciencedirect.com/science/article/pii/S1742706119307470

BibTex

@article{BUT161332,
  author="Tereza {Vaněčková} and Jaroslava {Bezděková} and Gang {Han} and Vojtěch {Adam} and Markéta {Vaculovičová}",
  title="Application of molecularly imprinted polymers as artificial receptors for imaging",
  journal="Acta Biomaterialia",
  year="2020",
  volume="101",
  number="1",
  pages="444--458",
  doi="10.1016/j.actbio.2019.11.007",
  issn="1742-7061",
  url="https://www.sciencedirect.com/science/article/pii/S1742706119307470"
}