Publication detail

Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

ŠŤASTNÝ, P. CHLUP, Z. KALASOVÁ, D. ZIKMUND, T. KAISER, J. TRUNEC, M.

Original Title

Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

English Title

Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

Type

journal article in Web of Science

Language

en

Original Abstract

Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430 µm, and the most frequent interconnecting pore window size 150 µm, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3 MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured.

English abstract

Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430 µm, and the most frequent interconnecting pore window size 150 µm, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3 MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured.

Keywords

foams gelcasting hydroxyapatite mills/milling scaffold

Released

01.08.2018

Publisher

Wiley online library

ISBN

0002-7820

Periodical

Journal of the American Ceramic Society

Year of study

101

Number

8

State

US

Pages from

3317

Pages to

3327

Pages count

11

URL

Documents

BibTex


@article{BUT148051,
  author="Přemysl {Šťastný} and Zdeněk {Chlup} and Dominika {Kalasová} and Tomáš {Zikmund} and Jozef {Kaiser} and Martin {Trunec}",
  title="Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications",
  annote="Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430 µm, and the most frequent interconnecting pore window size 150 µm, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3 MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured.",
  address="Wiley online library",
  chapter="148051",
  doi="10.1111/jace.15523",
  howpublished="print",
  institution="Wiley online library",
  number="8",
  volume="101",
  year="2018",
  month="august",
  pages="3317--3327",
  publisher="Wiley online library",
  type="journal article in Web of Science"
}