Publication detail

Deposition of glass fibers in a physically realistic replica of the human respiratory tract

BĚLKA, M. LÍZAL, F. JEDELSKÝ, J. ELCNER, J. HOPKE, P. JÍCHA, M.

Original Title

Deposition of glass fibers in a physically realistic replica of the human respiratory tract

English Title

Deposition of glass fibers in a physically realistic replica of the human respiratory tract

Type

journal article in Web of Science

Language

en

Original Abstract

Regional deposition of glass fibers was investigated in a physically realistic, human respiratory tract replica. The replica begins with the oral cavity and includes the airways up to the 7th generation of the tracheobronchial tree. Uniform diameter glass fibers were classified by length using a dielectrophoretic classifier and introduced into the replica at three steady-state flow rates (15, 30, and 50 LPM). A novel automatic image processing method was utilized to speed up the sample analysis and make it more reproducible. Fractional deposition was high in the oral cavity and the upper respiratory airways. Deposition density was higher in the first few generations of the tracheobronchial tree. Deposition efficiencies were compared with published data and good agreement was obtained. Our data confirmed that the deposition efficiency increased with increasing Stokes number indicating that impaction was the main deposition mechanism. The experimental data were used to propose new empirical models predicting fiber deposition in the tracheobronchial tree.

English abstract

Regional deposition of glass fibers was investigated in a physically realistic, human respiratory tract replica. The replica begins with the oral cavity and includes the airways up to the 7th generation of the tracheobronchial tree. Uniform diameter glass fibers were classified by length using a dielectrophoretic classifier and introduced into the replica at three steady-state flow rates (15, 30, and 50 LPM). A novel automatic image processing method was utilized to speed up the sample analysis and make it more reproducible. Fractional deposition was high in the oral cavity and the upper respiratory airways. Deposition density was higher in the first few generations of the tracheobronchial tree. Deposition efficiencies were compared with published data and good agreement was obtained. Our data confirmed that the deposition efficiency increased with increasing Stokes number indicating that impaction was the main deposition mechanism. The experimental data were used to propose new empirical models predicting fiber deposition in the tracheobronchial tree.

Keywords

Fiber deposition Human respiratory airways Glass fibers Experiments Deposition measurement

Released

01.03.2018

Publisher

Elsevier SCI LTD

Location

England

Pages from

1

Pages to

15

Pages count

15

URL

Documents

BibTex


@article{BUT143302,
  author="Miloslav {Bělka} and František {Lízal} and Jan {Jedelský} and Jakub {Elcner} and Philip K. {Hopke} and Miroslav {Jícha}",
  title="Deposition of glass fibers in a physically realistic replica of the human respiratory tract",
  annote="Regional deposition of glass fibers was investigated in a physically realistic, human respiratory tract replica. The replica begins with the oral cavity and includes the airways up to the 7th generation of the tracheobronchial tree. Uniform diameter glass fibers were classified by length using a dielectrophoretic classifier and introduced into the replica at three steady-state flow rates (15, 30, and 50 LPM). A novel automatic image processing method was utilized to speed up the sample analysis and make it more reproducible. Fractional deposition was high in the oral cavity and the upper respiratory airways. Deposition density was higher in the first few generations of the tracheobronchial tree. Deposition efficiencies were compared with published data and good agreement was obtained. Our data confirmed that the deposition efficiency increased with increasing Stokes number indicating that impaction was the main deposition mechanism. The experimental data were used to propose new empirical models predicting fiber deposition in the tracheobronchial tree.",
  address="Elsevier SCI LTD",
  chapter="143302",
  doi="10.1016/j.jaerosci.2017.11.006",
  howpublished="online",
  institution="Elsevier SCI LTD",
  number="1",
  year="2018",
  month="march",
  pages="1--15",
  publisher="Elsevier SCI LTD",
  type="journal article in Web of Science"
}