Publication detail

Cyclopropylamine plasma polymers for increased cell adhesion and growth

MANAKHOV, A. LANDOVÁ, M. MEDALOVÁ, J. MICHLÍČEK, M. POLČÁK, J. NEČAS, D. ZAJÍČKOVÁ, L.

Original Title

Cyclopropylamine plasma polymers for increased cell adhesion and growth

Type

journal article in Web of Science

Language

English

Original Abstract

Plasma polymers with NHx groups were deposited from cyclopropylamine in low pressure radio frequency (RF) discharges. The amount of NHx decreased with increasing average power Pav, whereas the layer dissolution in water decreased and high Pav led to a slight film swelling. The C2C12 cells demonstrated very high adhesion to the layers regardless of the deposition conditions. Although the surface chemistry of amine-rich layers should enhance the cell proliferation, the WST-1 assay, and immunocytochemistry revealed lower cell proliferation and viability on the layers exhibiting above 18% of relative thickness loss in water. Promising results were obtained on the layers with better water stability and bearing 7–10% of NHx.

Keywords

amine coatings; cell adhesion; cyclopropylamine; ESCA/XPS;, pulsed discharges

Authors

MANAKHOV, A.; LANDOVÁ, M.; MEDALOVÁ, J.; MICHLÍČEK, M.; POLČÁK, J.; NEČAS, D.; ZAJÍČKOVÁ, L.

Released

18. 7. 2017

ISBN

1612-8869

Periodical

Plasma Processes and Polymers

Year of study

14

Number

7

State

Federal Republic of Germany

Pages from

e1600123-1

Pages to

e1600123-1

Pages count

12