Publication detail

Preparation and Characterization of Liposomes as Cosmetic Delivery Systems

BOKROVÁ, J. MATOUŠKOVÁ, P. TILŠAROVÁ, K. MÁROVÁ, I.

Original Title

Preparation and Characterization of Liposomes as Cosmetic Delivery Systems

English Title

Preparation and Characterization of Liposomes as Cosmetic Delivery Systems

Language

en

Original Abstract

Besides finding some new sources, cosmetic producers tend to adopt well-known and popular ingredients already used in the health and food sectors. Presented work is focused on characterization of some complex natural sources of phenolics and their encapsulation into liposome nanoparticles. Total phenolics, flavonoids and antioxidant activity of plant extracts was determined spectrophotometrically. Extracts were then packed into liposome particles. Size of prepared liposomes was evaluated by dynamic light scattering and their stability was determined using zeta potential. Encapsulation efficiency of active compounds was evaluated by spectrophotometrical methods. Liposome particles with antioxidant properties were tested for possible genotoxic effects as well as pure extracts. In this work it was found that selected natural sources of phenolics could be packed into liposome particles with high encapsulation efficiency. Neither prepared particles nor pure extracts show genotoxic effect on model organism. Liposome particles with antioxidant ingredients can enhance the effectiveness of cosmetic products and could be also used in modern food supplements.

English abstract

Besides finding some new sources, cosmetic producers tend to adopt well-known and popular ingredients already used in the health and food sectors. Presented work is focused on characterization of some complex natural sources of phenolics and their encapsulation into liposome nanoparticles. Total phenolics, flavonoids and antioxidant activity of plant extracts was determined spectrophotometrically. Extracts were then packed into liposome particles. Size of prepared liposomes was evaluated by dynamic light scattering and their stability was determined using zeta potential. Encapsulation efficiency of active compounds was evaluated by spectrophotometrical methods. Liposome particles with antioxidant properties were tested for possible genotoxic effects as well as pure extracts. In this work it was found that selected natural sources of phenolics could be packed into liposome particles with high encapsulation efficiency. Neither prepared particles nor pure extracts show genotoxic effect on model organism. Liposome particles with antioxidant ingredients can enhance the effectiveness of cosmetic products and could be also used in modern food supplements.

Keywords

liposomes, phenolics, genotoxicity

Released

23.03.2017

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Brno

Pages from

144

Pages to

148

Pages count

5

BibTex


@inproceedings{BUT138000,
  author="Jitka {Bokrová} and Petra {Matoušková} and Kamila {Tilšarová} and Ivana {Márová}",
  title="Preparation and Characterization of Liposomes as Cosmetic Delivery Systems",
  annote="Besides finding some new sources, cosmetic producers tend to adopt well-known and popular ingredients already used in the health and food sectors.
 Presented work is focused on characterization of some complex natural sources of phenolics and their encapsulation into liposome nanoparticles.
Total phenolics, flavonoids and antioxidant activity of plant extracts was determined spectrophotometrically.  Extracts were then packed into liposome particles. Size of prepared liposomes was evaluated by dynamic light scattering and their stability was determined using zeta potential. Encapsulation efficiency of active compounds was evaluated by spectrophotometrical methods. Liposome particles with antioxidant properties were tested for possible genotoxic effects as well as pure extracts. 
In this work it was found that selected natural sources of phenolics could be packed into liposome particles with high encapsulation efficiency. Neither prepared particles nor pure extracts show genotoxic effect on model organism. Liposome particles with antioxidant ingredients can enhance the effectiveness of cosmetic products and could be also used in modern food supplements.
",
  address="Vysoké učení technické v Brně, Fakulta chemická",
  chapter="138000",
  howpublished="electronic, physical medium",
  institution="Vysoké učení technické v Brně, Fakulta chemická",
  year="2017",
  month="march",
  pages="144--148",
  publisher="Vysoké učení technické v Brně, Fakulta chemická"
}