Publication detail

Molecular docking study of potential drug candidates against borreliosis

KOŠČOVÁ, P.

Original Title

Molecular docking study of potential drug candidates against borreliosis

Type

conference paper

Language

English

Original Abstract

Lyme borreliosis is one of the most common tick-borne infections, for which there is an extensive need to find a new drug. For this purpose our in silicodocking study was carried out to identify drug-likeness of chosen small molecules –potential borreliosis drugs. Its results revealed that BesA compound (C2 form) – a membrane fusion protein present in Borrelia burgdorferi, can play a significant role as a possible drug target compound and therefore it should be further examined in development of potential drugs for Lyme borreliosis treatment.

Keywords

Borrelia burgdorferi, borreliosis, Lyme disease, resistance, molecular docking

Authors

KOŠČOVÁ, P.

Released

27. 4. 2017

Publisher

Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií

Location

Brno

ISBN

978-80-214-5496-5

Book

Proceedings of the 23rd Conference STUDENT EEICT 2017

Pages from

339

Pages to

343

Pages count

5

BibTex

@inproceedings{BUT135396,
  author="Pavlína {Cicková}",
  title="Molecular docking study of potential drug candidates against borreliosis",
  booktitle="Proceedings of the 23rd Conference STUDENT EEICT 2017",
  year="2017",
  pages="339--343",
  publisher="Vysoké učení technické v Brně, Fakulta elektrotechniky a komunikačních technologií",
  address="Brno",
  isbn="978-80-214-5496-5"
}