Publication detail

The Electrochemical Oxidation of Paracetamol and Its Voltammetric Sensing in Biological Samples Based on Screen Printed Graphene Electrodes

FERNANDEZ, C. HEGER, Z. KIZEK, R. RAMAKRISHNAPPA, T. BORUN, A. FAISAL, N.

Original Title

The Electrochemical Oxidation of Paracetamol and Its Voltammetric Sensing in Biological Samples Based on Screen Printed Graphene Electrodes

Type

journal article in Web of Science

Language

English

Original Abstract

We present a sensitive, fast and unmodified sensor for the electrochemical detection of paracetamol. The electrochemical behaviours of paracetamol on screen printed graphene electrodes were investigated for the first time by cyclic voltammetry. The results showed that the screen printed graphene electrodes revealed exceptional electrocatalytic activity to paracetamol. The response showed by this sensor was enhanced when it was compared to the bare screen printed electrodes. When Screen Printed Graphene Electrodes were compared to bare SPE, it was shown that the response with graphene was greater than without. This is due to its unique characteristics physical and chemical, π-π interactions and a strong adsorptive capability. In this manuscript, the effect of supporting electrolyte, pH and scan rate were also investigated. The oxidation peak current was linearly proportional to the concentration of paracetamol in the range from 0.1 to 50 μM with a limit of detection of 20nM based on (3-σ/slope), under the optimum conditions. The proposed method was successfully applied to paracetamol determination in in biological samples such as human oral fluid.

Keywords

Paracetamol; Electrochemical Sensor; Real Samples; Screen Printed Graphene Electrodes

Authors

FERNANDEZ, C.; HEGER, Z.; KIZEK, R.; RAMAKRISHNAPPA, T.; BORUN, A.; FAISAL, N.

RIV year

2015

Released

28. 7. 2015

ISBN

1452-3981

Periodical

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE

Year of study

10

Number

9

State

Republic of Serbia

Pages from

7440

Pages to

7452

Pages count

13

BibTex

@article{BUT118705,
  author="Carlos {Fernandez} and Zbyněk {Heger} and René {Kizek} and Thippeswamy {Ramakrishnappa} and Agnieszka {Borun} and Nadimul {Faisal}",
  title="The Electrochemical Oxidation of Paracetamol and Its Voltammetric Sensing in Biological Samples Based on Screen Printed Graphene Electrodes",
  journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE",
  year="2015",
  volume="10",
  number="9",
  pages="7440--7452",
  issn="1452-3981"
}