Patent detail

Process for making fingolimod

Reinerus Gerardus Gieling, Jozef Krajcovic

Patent type

Patent

Abstract

The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acidaddition salt, to compounds of formula (11) and (14) and their use in making fingolimod.

Patent number

WO2012041359A1

Date of application

1. 10. 2010

Date of registration

5. 4. 2012

Publisher

Úřad průmyslového vlastnictví (patentový úřad České republiky)

Owner

SYNTHON B.V. Microweg 22 NL-6545 CM Nijmegen

Possibilities of use

In order to use the result by another entity, it is always necessary to acquire a license

Licence fee

The licensor does not require a license fee for the result