Publication detail

Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery

BLAŽKOVÁ, I. NGUYEN, H. DOSTÁLOVÁ, S. KOPEL, P. STANISAVLJEVIC, M. VACULOVIČOVÁ, M. STIBOROVÁ, M. ECKSCHLAGER, T. KIZEK, R. ADAM, V.

Original Title

Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery

Type

journal article in Web of Science

Language

English

Original Abstract

Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution

Keywords

Magnetic particle, doxorubicin, fluorescence spectroscopy,

Authors

BLAŽKOVÁ, I.; NGUYEN, H.; DOSTÁLOVÁ, S.; KOPEL, P.; STANISAVLJEVIC, M.; VACULOVIČOVÁ, M.; STIBOROVÁ, M.; ECKSCHLAGER, T.; KIZEK, R.; ADAM, V.

RIV year

2013

Released

27. 6. 2013

Publisher

MDPI

ISBN

1422-0067

Periodical

International Journal of Molecular Sciences

Year of study

14

Number

7

State

Swiss Confederation

Pages from

13391

Pages to

13402

Pages count

11

URL

http://www.mdpi.com/1422-0067/14/7/13391

Full text in the Digital Library

http://hdl.handle.net/11012/70079

BibTex

@article{BUT100937,
  author="Iva {Blažková} and Hoai Viet {Nguyen} and Simona {Dostálová} and Pavel {Kopel} and Maja {Stanisavljevic} and Markéta {Vaculovičová} and Marie {Stiborová} and Tomáš {Eckschlager} and René {Kizek} and Vojtěch {Adam}",
  title="Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery",
  journal="International Journal of Molecular Sciences",
  year="2013",
  volume="14",
  number="7",
  pages="13391--13402",
  doi="10.3390/ijms140713391",
  issn="1422-0067",
  url="http://www.mdpi.com/1422-0067/14/7/13391"
}