Project detail

Cell Interactions with 3D Porous Collagenous Matrices Investigated by Coherence-Controlled Holographic Microscopy

Duration: 01.03.2019 — 28.02.2020

On the project

In the presented study, we would like to examine cell interactions in 3D environment of porous collagenous matrices using the non-invasive, label-free technique of coherence-controlled holographic microscopy. Moreover, these materials will be enriched by various bioactive substances resulting in different effect on cellular activity and interactions with collagen substrate. The results should bring up new knowledge about cell-to-matrix interactions of dermal cells with 3D-structured biosubstrates and help the promotion of coherence-controlled holographic microscopy in tissue engineering.


CEITEC VUT-J-19-6086

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People responsible

Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher
Dorazilová Jana, Ing. - principal person responsible


Funding resources

Brno University of Technology - Vnitřní projekty VUT

- whole funder (2019-01-01 - 2020-12-31)


DORAZILOVÁ, J.; MUCHOVÁ, J.; ŠMERKOVÁ, K.; KOČIOVÁ, S.; DIVIŠ, P.; KOPEL, P.; VESELÝ, R.; PAVLIŇÁKOVÁ, V.; ADAM, V.; VOJTOVÁ, L. Synergistic Effect of Chitosan and Selenium Nanoparticles on Biodegradation and Antibacterial Properties of Collagenous Scaffolds Designed for Infected Burn Wounds. Nanomaterials, 2020, vol. 10, no. 10, p. 1971-1992. ISSN: 2079-4991.

DORAZILOVÁ, J.; ŠTRBKOVÁ, l.; ĎURIŠ, M.; VOJTOVÁ, L. Biopolymeric scaffold for cell visualisation in 3D environment using Coherence-controlled holographic microscopy. 28th Biomaterials in Medicine and Veterinary Medicine, Annual Conference. Engineering of Biomaterials - Inżynieria Biomateriałów. Kraków: Scientific Publishing House AKAPIT, 2019. p. 43-43. ISSN: 1429-7248.