Detail publikace

A New Approach to Define Dynamics of the Ion Channel Gates

OZER, M., ERDEM, R., PROVAZNÍK, I.

Originální název

A New Approach to Define Dynamics of the Ion Channel Gates

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

Voltage-gated ion channels are of great importance in the generation and propagation of electrical signals in the excitable cellmembranes. How these channels respond to changes in the potential across themembrane has been a challenging problem, and different approaches have been proposed to address the mechanism of voltage sensing and gating in these channels. In this study, we attempt a new approach by considering a simple two-state gate system and applying the path probability method to construct a nonequilibrium statistical mechanical model of the system. The model which is based on the principles of statistical physics provides a firm physical basis for ion channel gating.

Klíčová slova

(In)Activation gate; Ion channel; Path probability method; Statistical mechanics

Autoři

OZER, M., ERDEM, R., PROVAZNÍK, I.

Rok RIV

2004

Vydáno

1. 2. 2004

Nakladatel

Lippincott Williams & Wilkins

ISSN

0959-4965

Periodikum

Neuroreport

Ročník

15

Číslo

2

Stát

Spojené státy americké

Strany od

335

Strany do

338

Strany počet

4

BibTex

@article{BUT41553,
  author="Mahmut {Ozer} and Riza {Erdem} and Valentine {Provazník}",
  title="A New Approach to Define Dynamics of the Ion Channel Gates",
  journal="Neuroreport",
  year="2004",
  volume="15",
  number="2",
  pages="4",
  issn="0959-4965"
}