Detail publikace

Patient-Ventilator Interaction Testing Using the Electromechanical Lung Simulator xPULM (TM) during V/A-C and PSV Ventilation Mode

PAŠTĚKA, R. SANTOS, P. BARROS, N. KOLÁŘ, R. FORJAN, M.

Originální název

Patient-Ventilator Interaction Testing Using the Electromechanical Lung Simulator xPULM (TM) during V/A-C and PSV Ventilation Mode

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

During mechanical ventilation, a disparity between flow, pressure and volume demands of the patient and the assistance delivered by the mechanical ventilator often occurs. This paper introduces an alternative approach of simulating and evaluating patient-ventilator interactions with high fidelity using the electromechanical lung simulator xPULM (TM). The xPULM (TM) approximates respiratory activities of a patient during alternating phases of spontaneous breathing and apnea intervals while connected to a mechanical ventilator. Focusing on different triggering events, volume assist-control (V/A-C) and pressure support ventilation (PSV) modes were chosen to test patient-ventilator interactions. In V/A-C mode, a double-triggering was detected every third breathing cycle, leading to an asynchrony index of 16.67%, which is classified as severe. This asynchrony causes a significant increase of peak inspiratory pressure (7.96 +/- 6.38 vs. 11.09 +/- 0.49 cmH(2)O, p < 0.01)) and peak expiratory flow (-25.57 +/- 8.93 vs. 32.90 +/- 0.54 L/min, p < 0.01) when compared to synchronous phases of the breathing simulation. Additionally, events of premature cycling were observed during PSV mode. In this mode, the peak delivered volume during simulated spontaneous breathing phases increased significantly (917.09 +/- 45.74 vs. 468.40 +/- 31.79 mL, p < 0.01) compared to apnea phases. Various dynamic clinical situations can be approximated using this approach and thereby could help to identify undesired patient-ventilation interactions in the future. Rapidly manufactured ventilator systems could also be tested using this approach.

Klíčová slova

biomedical engineering; breathing simulation; electromechanical lung simulator; patient– ventilator interactions; rapidly manufactured ventilator systems testing

Autoři

PAŠTĚKA, R.; SANTOS, P.; BARROS, N.; KOLÁŘ, R.; FORJAN, M.

Vydáno

21. 4. 2021

Nakladatel

MDPI

Místo

BASEL

ISSN

2076-3417

Periodikum

Applied Sciences - Basel

Ročník

11

Číslo

9

Stát

Švýcarská konfederace

Strany od

1

Strany do

14

Strany počet

14

URL

https://www.mdpi.com/2076-3417/11/9/3745

Plný text v Digitální knihovně

http://hdl.handle.net/11012/201666

BibTex

@article{BUT172367,
  author="Richard {Paštěka} and Pedro {Santos} and Nelson {Barros} and Radim {Kolář} and Mathias {Forjan}",
  title="Patient-Ventilator Interaction Testing Using the Electromechanical Lung Simulator xPULM (TM) during V/A-C and PSV Ventilation Mode",
  journal="Applied Sciences - Basel",
  year="2021",
  volume="11",
  number="9",
  pages="1--14",
  doi="10.3390/app11093745",
  issn="2076-3417",
  url="https://www.mdpi.com/2076-3417/11/9/3745"
}